Myelin PLP Antibody

Western Blot: Myelin PLP Antibody [H00005354-D01P] - Analysis of PLP1 expression in transfected 293T cell line by PLP1 polyclonal antibody.Lane 1: PLP1 transfected lysate(30.10 KDa).Lane 2: Non-transfected lysate.

Western Blot: Myelin PLP Antibody [H00005354-D01P] - PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in A-431.

Western Blot: Myelin PLP Antibody [H00005354-D01P] - PLP1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLP1 expression in mouse testis.

Product Discontinued

Myelin PLP Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PLP1 (NP_000524.3, 1 a.a. - 277 a.a.) full-length human protein. MGLLECCARCLVGAPFASLVATGLCFFGVALFCGCGHEALTGTEKLIETYFSKNYQDYEYLINVIHAFQYVIYGTASFFFLYGALLLAEGFYTTGAVRQIFGDYKTTICGKGLSATVTGGQKGRGSRGQHQAHSLERVCHCLGKWLGHPDKFVGITYALTVVWLLVFACSAVPVYIYFNTWTTCQSIAFPSKTSASIGSLCADARMYGVLPWNAFPGKVCGSNLLSICKTAEFQMTFHLFIAAFVGAAATLVSLLTFMIAATYNFAVLKLMGRGTKF
• Marker: Oligodendrocyte Marker
• Specificity: PLP1 - proteolipid protein 1 (Pelizaeus-Merzbacher disease, spastic paraplegia 2, uncomplicated),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLP1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Myelin PLP Antibody

• DM-20
• HLD1
• Lipophilin
• major myelin proteolipid protein
• MMPL
• Myelin PLP
• myelin proteolipid protein
• PLP
• PLP/DM20
• PLP1
• PMD
• proteolipid protein 1
• spastic paraplegia 2, uncomplicated
• SPG2

Background

This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLP1
• Entrez:
  • 5354(Human)
• Uniprot:
  • NP_000524.3(Human)