MTA2 Antibody Blocking Peptide

Western Blot: MTA2 Peptide [NBP1-76748PEP] - blocks the antibody activity completely in Western blot by incubating the peptide with equal volume of antibody for 30 min at 37C

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

MTA2 Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 17 amino acids of human PID.

  Source: Synthetic

  (Accession #: AAG02241)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: MTA2
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76748. For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for MTA2 Antibody Blocking Peptide

• DKFZp686F2281
• metastasis associated 1 family, member 2
• metastasis -associated gene 1-like 1
• metastasis associated gene family, member 2
• Metastasis-associated 1-like 1
• metastasis-associated protein 2
• metastasis-associated protein MTA2
• MTA1-L1 protein
• MTA1L1MTA1-L1
• p53 target protein in deacetylase complex
• PID

Background

Official Gene Symbol: MTA2 Gen Bank Accession Number: NP_004730 Gene ID: 9219 (Human) Gene Map Locus: 11q12-q13.1 (human) MTA2, a homologue of human MTA1 and MTA3, is a member of highly conserved MTA gene family. It is a component of NuRD, an ATP-dependent nucleosome remodeling and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependant transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of Estrogen receptor-alpha. Northern Blot analysis detected a ubiquitous expression of MTA2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: MTA2