MTA2 Products

Antibodies
Proteins
Recombinant Human MTA2 GST (N ...
Recombinant Human MTA2 GST (N-Term...
H00009219-Q01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human MTA2 GST (N ...
Recombinant Human MTA2 GST (N-Term...
H00009219-P01
Species: Hu
Applications: WB, ELISA, PA, AP
MTA2 Antibody Blocking Peptid ...
MTA2 Antibody Blocking Peptide
NBP1-76748PEP
Species: Hu
Applications: AC

Description

Official Gene Symbol: MTA2 Gen Bank Accession Number: NP_004730 Gene ID: 9219 (Human) Gene Map Locus: 11q12-q13.1 (human) MTA2, a homologue of human MTA1 and MTA3, is a member of highly conserved MTA gene family. It is a component of NuRD, an ATP-dependent nucleosome remodeling and histone deacetylase complex. MTA2 is a nuclear protein that interacts with HDAC1 and HDAC2 and has a functional role in chromatin remodeling and deacetylase activity. MTA2 specifically interacts with p53 and represses p53-dependant transcriptional activation, thereby regulating p53-mediated cell growth arrest and apoptosis. It also inhibits the transcriptional activity of Estrogen receptor-alpha. Northern Blot analysis detected a ubiquitous expression of MTA2.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 9219
Alternate Names
  • metastasis-associated protein MTA2
  • MTA1-L1 protein
  • metastasis-associated protein 2
  • PID
  • metastasis -associated gene 1-like 1
  • Metastasis-associated 1-like 1
  • DKFZp686F2281
  • metastasis associated gene family, member 2
  • MTA1L1MTA1-L1
  • p53 target protein in deacetylase complex
  • metastasis associated 1 family, member 2

Research Areas for MTA2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
Phospho-Specific
Transcription Factors and Regulators
Tumor Suppressors

Bioinformatics Tool for MTA2

Discover related pathways, diseases and genes to MTA2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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