MSX1 Antibody (801601) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: IHC
• Clone: 801601
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

MSX1 Antibody (801601) [Alexa Fluor® 750] Summary

• Immunogen: E. coli-derived recombinant human MSX1
  Met1-Thr165
  Accession # P28360
• Specificity: Detects human MSX1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human MSX2 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MSX1 Antibody (801601) [Alexa Fluor® 750]

• Homeobox protein Hox-7
• homeobox protein MSX-1
• HOX7
• HOX7homeobox 7
• HYD1
• HYD1msh homeobox homolog 1 (Drosophila)
• msh (Drosophila) homeo box homolog 1 (formerly homeo box 7)
• msh homeo box 1
• msh homeobox 1
• Msh homeobox 1-like protein
• msh homeobox homolog 1
• MSX1
• OFC5
• STHAG1

Background

MSX1 (Msh homeobox homology 1) is a member of the muscle segment homoebox gene family. MSX1 is involved in limb-pattern formation, craniofacial development, odontogenesis, and tumor growth inhibition. MSX1 functions as a transcriptional repressor. MSX1 has been shown to interact with the linker histone, H1B, and repress transcription of the MyoD promoter. Chromosomal abnormalities involving MSX1 have been associated with the Wolf-Hirschhorn syndrome characterized by heart defects and mental retardation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.