MRP4/ABCC4 Antibody (M4I-10)

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr
Clone
M4I-10
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
.015 mg/ml

Order Details

MRP4/ABCC4 Antibody (M4I-10) Summary

Immunogen
The antibody reacts with the MRP4 antigen.
Specificity
The M4I-10 Mab was selected after immunization with a fusion protein containing the E. coli maltose binding protein and a fragment of the human MRP4 protein corresponding to amino acids 372-431. MRP4 transports cyclic nucleotides and anti-retroviral compounds. The M4I-10 Mab also reacts with the mouse orthologue of the transporter molecule (Mrp4).
Isotype
IgG2a
Clonality
Monoclonal
Host
Rat
Gene
ABCC4
Purity
Tissue culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Application Notes
Immunocytochemistry: use 1:20-50 dil. on acetone fixed cytospin preparations. For immunohistochemistry: M4I- 10 (use 1:20) on acetone fixed frozen sections can be followed by incubation with biotin-labeled rabbit anti-rat IgG (1:100) and HRP-labeled
Publications
Read Publication using NBP1-42339.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Serum - free culture supernatant with 0.7% BSA
Preservative
0.1% Sodium Azide
Concentration
.015 mg/ml
Purity
Tissue culture supernatant

Alternate Names for MRP4/ABCC4 Antibody (M4I-10)

  • ABCC4
  • ATP-binding cassette sub-family C member 4
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 4
  • EST170205
  • MOATB
  • MOAT-BbA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
  • MOATBcanalicular multispecific organic anion transporter (ABC superfamily)
  • MRP4
  • MRP4MRP/cMOAT-related ABC transporter
  • multidrug resistance-associated protein 4
  • multispecific organic anion transporter B
  • Multi-specific organic anion transporter B

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MRP4/ABCC4 Antibody (NBP1-42339)(1)


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Bioinformatics

Gene Symbol ABCC4