MRP4/ABCC4 Antibody (M4I-10)

• Reactivity: Hu, Mu
• Applications: WB, Flow, ICC/IF, IHC
• Clone: M4I-10
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: .015 mg/ml

MRP4/ABCC4 Antibody (M4I-10) Summary

• Description: Novus Biologicals Rat MRP4/ABCC4 Antibody (M4I-10) (NBP1-42339) is a monoclonal antibody validated for use in IHC, WB, Flow and ICC/IF. Anti-MRP4/ABCC4 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Maltose Binding Protein and aa 372-431 of MRP4/ABCC4
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: ABCC4
• Purity: Tissue culture supernatant

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:20
  • Immunohistochemistry-Frozen 1:20
  • Western Blot 1:50
• Application Notes: Immunocytochemistry: use 1:20-50 dil. on acetone fixed cytospin preparations. For immunohistochemistry: M4I- 10 (use 1:20) on acetone fixed frozen sections can be followed by incubation with biotin-labeled rabbit anti-rat IgG (1:100) and HRP-labeled

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS, 0.1% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: .015 mg/ml
• Purity: Tissue culture supernatant

Alternate Names for MRP4/ABCC4 Antibody (M4I-10)

• ABCC4
• ATP-binding cassette sub-family C member 4
• ATP-binding cassette, sub-family C (CFTR/MRP), member 4
• EST170205
• MOATB
• MOAT-BbA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
• MOATBcanalicular multispecific organic anion transporter (ABC superfamily)
• MRP4
• MRP4MRP/cMOAT-related ABC transporter
• multidrug resistance-associated protein 4
• multispecific organic anion transporter B
• Multi-specific organic anion transporter B

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MRP4/ABCC4 Antibody (NBP1-42339)(1)

Publication using NBP1-42339

• Nagy RA, Hollema H, Andrei D et al. The Origin of Follicular Bile Acids in the Human Ovary Am. J. Pathol. 2019-07-29 [PMID: 31369754]

Bioinformatics

• Gene Symbol: ABCC4