| Reactivity | HuSpecies Glossary |
| Clone | 464510 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Alexa Fluor Plus 647 |
| Specificity | Detects human MRP1. Detects human MRP1-transfected cells, but not irrelevant transfectants by flow cytometry. |
| Isotype | IgG2a |
| Clonality | Monoclonal |
| Host | Mouse |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied |
| Buffer | Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide. |
MRP1 (Multidrug Resistance associated Protein 1), also known as ABCC1, belongs to the family of ATP-Binding Cassette (ABC) transporters. It confers multidrug resistance on tumor cells and is overexpressed in various human multidrug resistant tumor cell lines.
Secondary Antibodies |
Isotype Controls |
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ABC Membrane transporters and the role of MRP1 in drug resistance ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes. Multidrug resistance-associated protein 1 (MRP1) is a member o... Read full blog post. |
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