MP1/MAP2K1IP1 Antibody - BSA Free

Western Blot: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue lysate with MP1/MAP2K1IP1 antibody at (A) 1 and (B) 2 ug/ml.

Immunocytochemistry/Immunofluorescence: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue with MP1/MAP2K1IP1 antibody at 20 ug/ml.

Immunohistochemistry: MP1/MAP2K1IP1 Antibody [NBP2-81886] - Analysis of MP1/MAP2K1IP1 in human brain tissue with MP1/MAP2K1IP1 antibody at 5 ug/ml.

• Reactivity: Hu, Mu, Rt, Bv, Ch
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

MP1/MAP2K1IP1 Antibody - BSA Free Summary

• Immunogen: MAP2K1IP1 antibody was raised against an 15 amino acid peptide near the center of human MAP2K1IP1. The immunogen is located within amino acids 40 - 90 of MAP2K1IP1. Amino Acid Squence: ATDQGSKLGLSKNKS
• Specificity: MP1/MAP2K1IP1 antibody is human, mouse and rat reactive. At least two isoforms of MP1/MAP2K1IP1 are known to exist; this antibody will detect both isoforms. MP1/MAP2K1IP1 antibody is predicted to not cross-react with other LAMTOR family proteins.
• Predicted Species: Bovine (100%), Chicken (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LAMTOR3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 20 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin
  • Western Blot 1-2 ug/ml
• Theoretical MW: 13 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for MP1/MAP2K1IP1 Antibody - BSA Free

• LAMTOR3
• Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3
• late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
• MAP2K1IP1
• Mapbp
• MAPK scaffold protein 1
• MAPKSP1
• MEK binding partner 1
• MEK partner 1
• MEK-binding partner 1
• mitogen-activated protein kinase kinase 1 interacting protein 1
• Mitogen-activated protein kinase kinase 1-interacting protein 1
• Mitogen-activated protein kinase scaffold protein 1
• MP1
• PRO0633
• Ragulator3

Background

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LAMTOR3