MP1/MAP2K1IP1 Products

Description

The function of MAP2K1IP1/MAPKSP1 (MP1;MEK partner-1) a 14kDa scaffold protein, is to bind specifically to MEK1 and ERK1 and bring them in close proximity in order to facilitate their activation. Localized to the late endosome, MAP2K1IP1 also interacts with an adaptor protein p14. While the interaction between MAPKSP1-ERK1 can take place in the absence of the adaptor protein p14, it is strengthened in the presence of p14. Additionally, it has been suggested that the binding of MAP2K1IP1/MAPKSP1 to MEK1 resides in a proline-rich sequence (residue 270-307) of MEK1.

Bioinformatics

Entrez	56692 Mouse 8649 Human
Uniprot	NM_021970 Human NP_068805 Human NP_068805.1 Human O88653 Mouse Q9UHA4 Human
Product By Gene ID	8649
Alternate Names	Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 MAP2K1IP1 MAPBP MAPK scaffold protein 1 MAPKSP1 MEK binding partner 1 MEK partner 1 MEK-binding partner 1 mitogen-activated protein kinase kinase 1 interacting protein 1 Mitogen-activated protein kinase kinase 1-interacting protein 1 Mitogen-activated protein kinase scaffold protein 1 Mp1 MP1 PRO0633 Ragulator3

Research Areas for MP1/MAP2K1IP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
Signal Transduction