Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Ccl2

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate

• C-C motif chemokine ligand 2
• CCL2
• GDCF-2
• HC11
• HSMCR30
• MCAF
• Mcp1
• MCP-1
• SCYA2
• SMC-CF

Background

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

Publications for CCL2/JE/MCP-1 (DY479)(176)

Publications using DY479

• Yang, J;Xu, B;Cao, J;Liu, Y;Tang, L;Zhao, P;Li, S;Li, X;Liu, J;Yu, R;Tang, Y;Tan, W;Ding, H;Li, J;Liu, Y; Characterizing the mechanisms underpinning interleukin-15R?-mediated protection against sepsis and candidiasis Cytokine 2025-09-17 [PMID: 40967153] (Mouse, Transgenic Mouse)
• Chang, KW;Chen, JT;Chuang, CN;Thi Thanh Thao, D;Huang, YT;Wu, HY;Kuo, ML;Kao, KC;Chiu, CH;Lai, CH; Microplastic exposure aggravates pneumococcus-induced inflammation in macrophages by activating ferroptosis Journal of hazardous materials 2025-08-29 [PMID: 40907312] (Mouse)
• Kumar, A;O'Brien, M;Young, VB;Yung, R; Single-cell RNA sequencing identifies accumulation of Fcgr2b+ virtual memory like CD8 T cells with cytotoxic and inflammatory potential in aged mouse white adipose tissue bioRxiv : the preprint server for biology 2025-06-30 [PMID: 40631318] (Mouse)
• Dean, LS;Wahl, M;Threatt, AN;Pauly, M;Barahona, M;Oyewole, EO;Nordgren, TM; Spectral immune cell profiling reveals modulations in immune cell response to repetitive inhaled organic dust exposure in a high omega-3 fatty acid mouse model Lipids in health and disease 2025-07-02 [PMID: 40604979] (Mouse)
• Adamowicz, K;Lima Ribeiro, AS;Golda, A;Wadowska, M;Potempa, J;Schmaderer, C;Anders, HJ;Koziel, J;Lech, M; Bidirectional Interaction Between Chronic Kidney Disease and Porphyromonas gingivalis Infection Drives Inflammation and Immune Dysfunction Journal of immunology research 2025-04-17 [PMID: 40276114] (Mouse)
• Hu, Z;Deshmukh, M;Jarneborn, A;Bollmann, M;Corciulo, C;Kopparapu, PK;Ali, A;Svensson, MND;Engdahl, C;Pullerits, R;Mohammad, M;Jin, T; Combination treatment with anti-RANKL and antibiotics for preventing joint destruction in septic arthritis JCI insight 2025-03-24 [PMID: 40067374] (Mouse)
• Faizan, MI;Kaur, G;Shaikh, SB;Effah, F;Unwalla, H;Rahman, I; Genetic diversity leads to differential inflammatory responses to cigarette smoke in mice Physiological reports 2025-01-01 [PMID: 39844449] (Mouse)
• Hamadi, N;Al?Salam, S;Beegam, S;Zaaba, N;Elzaki, O;Nemmar, A; Chronic Exposure to Two Regimens of Waterpipe Smoke Elicits Lung Injury, Genotoxicity, and Mitochondrial Impairment with the Involvement of MAPKs Activation in Mice International journal of molecular sciences 2025-01-06 [PMID: 39796284] (Mouse)
• Pinto, LG;Vilar, B;McNaughton, PA; PGE2 and HCN2 ion channels are critical mediators of pain initiated by angiotensin II Brain, behavior, and immunity 2024-12-28 [PMID: 39736364] (Mouse)
• Cheung, EC;Strathdee, D;Stevenson, D;Coomes, J;Blyth, K;Vousden, KH; Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment Proceedings of the National Academy of Sciences of the United States of America 2024-12-10 [PMID: 39636862] (Mouse)
• Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J; Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice JCI insight 2024-09-10 [PMID: 39253972] (Mouse, Transgenic Mouse)
• Nayer, B;Tan, JL;Alshoubaki, YK;Lu, YZ;Legrand, JMD;Lau, S;Hu, N;Park, AJ;Wang, XN;Amann-Zalcenstein, D;Hickey, PF;Wilson, T;Kuhn, GA;Müller, R;Vasanthakumar, A;Akira, S;Martino, MM; Local administration of regulatory T cells promotes tissue healing Nature communications 2024-09-09 [PMID: 39251592] (Mouse)
• Gabele, L;Bochow, I;Rieke, N;Sieben, C;Michaelsen-Preusse, K;Hosseini, S;Korte, M; H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro Frontiers in cellular neuroscience 2024-08-07 [PMID: 39171200] (Mouse)
• Galley, JD;King, MK;Rajasekera, TA;Batabyal, A;Woodke, ST;Gur, TL; Gestational administration of Bifidobacterium dentium results in intergenerational modulation of inflammatory, metabolic, and social behavior Brain, behavior, and immunity 2024-08-12 [PMID: 39128569] (Mouse)
• Sun, L;Apweiler, M;Tirkey, A;Klett, D;Normann, C;Dietz, GPH;Lehner, MD;Fiebich, BL; Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells International journal of molecular sciences 2024-07-25 [PMID: 39125680] (Mouse)
• Lai, HC;Chen, PH;Tang, CH;Chen, LW; IL-10 Enhances the Inhibitory Effect of Adipose-Derived Stromal Cells on Insulin Resistance/Liver Gluconeogenesis by Treg Cell Induction International journal of molecular sciences 2024-07-25 [PMID: 39125659] (Mouse)
• Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y; Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota Heliyon 2024-07-15 [PMID: 39071618] (Mouse)
• Sun, L;Wilke Saliba, S;Apweiler, M;Akmermer, K;Herlan, C;Grathwol, C;de Oliveira, ACP;Normann, C;Jung, N;Bräse, S;Fiebich, BL; Anti-Neuroinflammatory Effects of a Macrocyclic Peptide-Peptoid Hybrid in Lipopolysaccharide-Stimulated BV2 Microglial Cells International journal of molecular sciences 2024-04-18 [PMID: 38674048] (Mouse)
• Mingo, YB;Gabele, L;Lonnemann, N;Brône, B;Korte, M;Hosseini, S; The effects of urolithin A on poly I:C-induced microglial activation Frontiers in cellular neuroscience 2024-03-20 [PMID: 38577490] (Mouse)
• Sluiter, TJ;Tillie, RJHA;de Jong, A;de Bruijn, JBG;Peters, HAB;van de Leijgraaf, R;Halawani, R;Westmaas, M;Starink, LIW;Quax, PHA;Sluimer, JC;de Vries, MR; Myeloid PHD2 Conditional Knockout Improves Intraplaque Angiogenesis and Vascular Remodeling in a Murine Model of Venous Bypass Grafting Journal of the American Heart Association 2024-01-23 [PMID: 38258662] (Transgenic Mouse)
• Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S; Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors Journal of neuroinflammation 2023-12-19 [PMID: 38111048] (Mouse)
• Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS; A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus Viruses 2023-10-04 [PMID: 37896826] (Mouse)
• Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J; Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice bioRxiv : the preprint server for biology 2023-09-29 [PMID: 37808846] (Mouse)
• Hou, C;Jiang, X;Sheng, W;Zhang, Y;Lin, Q;Hong, S;Zhao, J;Wang, T;Ye, X; Xinmaikang (XMK) tablets alleviate atherosclerosis by regulating the SREBP2-mediated NLRP3/ASC/Caspase-1 signaling pathway Journal of ethnopharmacology 2023-09-28 [PMID: 37777030] (Mouse)
• Manandhar, S;Chambers, S;Miller, A;Ishii, I;Bhatia, M; Pharmacological Inhibition and Genetic Deletion of Cystathionine Gamma-Lyase in Mice Protects against Organ Injury in Sepsis: A Key Role of Adhesion Molecules on Endothelial Cells International journal of molecular sciences 2023-09-04 [PMID: 37686458] (Mouse, Transgenic Mouse)
• Gschwandtner, M;Gammage, AN;Deligne, C;Mies, LFM;Domaingo, A;Murdamoothoo, D;Loustau, T;Schwenzer, A;Derler, R;Carapito, R;Koch, M;M�rgelin, M;Orend, G;Kungl, AJ;Midwood, KS; Investigating Chemokine-Matrix Networks in Breast Cancer: Tenascin-C Sets the Tone for CCL2 International journal of molecular sciences 2023-05-06 [PMID: 37176074] (Mouse)
• C Zhang, ZF Guo, W Liu, K Kazama, L Hu, X Sun, L Wang, H Lee, L Lu, XF Yang, R Summer, J Sun PIMT is a novel and potent suppressor of endothelial activation Elife, 2023-04-18;12(0):. 2023-04-18 [PMID: 37070640] (Mouse)
• KD Marshall, PJ Klutho, L Song, R Roy, M Krenz, CP Baines Cardiac Myocyte-Specific Overexpression of FASTKD1 Prevents Ventricular Rupture After Myocardial Infarction Journal of the American Heart Association, 2023-02-15;12(4):e025867. 2023-02-15 [PMID: 36789858] (Mouse, Transgenic Mouse)
• TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses Cell Reports, 2022-12-30;42(1):111905. 2022-12-30 [PMID: 36640342] (Mouse)
• DC Sarver, C Xu, LM Velez, S Aja, AE Jaffe, MM Seldin, RH Reeves, GW Wong Dysregulated systemic metabolism in a Down syndrome mouse model Molecular Metabolism, 2022-12-29;68(0):101666. 2022-12-29 [PMID: 36587842] (Mouse)
• K Chen, LY Cheong, Y Gao, Y Zhang, T Feng, Q Wang, L Jin, E Honoré, KSL Lam, W Wang, X Hui, A Xu Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects Nature Communications, 2022-12-20;13(1):7838. 2022-12-20 [PMID: 36539421] (Mouse)
• CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells Microbial pathogenesis, 2022-11-12;0(0):105881. 2022-11-12 [PMID: 36379373] (Mouse)
• K Tange, S Yagi, E Takeshita, M Abe, Y Yamamoto, H Tomida, T Kawamura, M Hanayama, B Matsuura, Y Ikeda, Y Hiasa Oral administration of human carbonic anhydrase I suppresses colitis in a murine inflammatory bowel disease model Scientific Reports, 2022-10-26;12(1):17983. 2022-10-26 [PMID: 36289244] (Mouse)
• Y Ji, Y Liang, PH Chu, M Ge, SC Yeung, MS Man Ip, JC Wo Mak The effects of intermittent hypoxia on hepatic expression of fatty acid translocase CD36 in lean and diet-induced obese mice Biomedical journal, 2022-10-13;0(0):. 2022-10-13 [PMID: 36244649] (Mouse)
• J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling Mediators of Inflammation, 2022-09-29;2022(0):3441357. 2022-09-29 [PMID: 36211988] (Mouse)
• R Gawish, B Maier, G Obermayer, ML Watzenboec, AD Gorki, F Quattrone, A Farhat, K Lakovits, A Hladik, A Korosec, A Alimohamma, I Mesteri, F Oberndorfe, F Oakley, J Brain, L Boon, I Lang, CJ Binder, S Knapp A neutrophil-B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4 Elife, 2022-09-30;11(0):. 2022-09-30 [PMID: 36178806] (Mouse)
• N Milad, M Pineault, F Tremblay, J Routhier, A Lechasseur, MJ Beaulieu, S Aubin, MC Morissette Smoking status impacts treatment efficacy in smoke-induced lung inflammation: A pre-clinical study Frontiers in Pharmacology, 2022-09-07;13(0):971238. 2022-09-07 [PMID: 36160400] (Mouse)
• F Seidel, R Kleemann, W van Duyven, N van Trigt, N Keijzer, S van der Ko, C van Kooten, L Verschuren, A Menke, AJ Kiliaan, J Winter, TR Hughes, BP Morgan, F Baas, K Fluiter, MC Morrison Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice International Journal of Molecular Sciences, 2022-09-14;23(18):. 2022-09-14 [PMID: 36142647] (Mouse)
• XY Choo, LE McInnes, A Grubman, JM Wasielewsk, I Belaya, E Burrows, H Quek, JC Martín, S Loppi, A Sorvari, D Rait, A Powell, C Duncan, JR Liddell, H Tanila, JM Polo, T Malm, KM Kanninen, PS Donnelly, AR White Novel Anti-Neuroinflammatory Properties of a Thiosemicarbazone-Pyridylhydrazone Copper(II) Complex International Journal of Molecular Sciences, 2022-09-14;23(18):. 2022-09-14 [PMID: 36142627] (Mouse)
• P Boroumand, DC Prescott, T Mukherjee, PJ Bilan, M Wong, J Shen, I Tattoli, Y Zhou, A Li, T Sivasubram, N Shi, LY Zhu, Z Liu, C Robbins, DJ Philpott, SE Girardin, A Klip Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity Elife, 2022-09-20;11(0):. 2022-09-20 [PMID: 36125130] (Mouse)
• J Lee, SY Ahn, CTT Le, DH Lee, J Jung, EJ Ko Protective and vaccine dose-sparing efficacy of Poly I:C-functionalized calcium phosphate nanoparticle adjuvants in inactivated influenza vaccination International immunopharmacology, 2022-09-14;112(0):109240. 2022-09-14 [PMID: 36115278] (Mouse)
• SJ Matissek, M Karbalivan, W Han, A Boutilier, E Yzar-Garci, LL Kehoe, DS Gardner, A Hage, K Fleck, V Jeffers, R Rajsbaum, SF Elsawa A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Oncotarget, 2022-08-03;13(0):944-959. 2022-08-03 [PMID: 35937499] (Mouse)
• J Faura, L Ramiro, A Simats, F Ma, A Penalba, T Gasull, A Rosell, J Montaner, A Bustamante Evaluation and Characterization of Post-Stroke Lung Damage in a Murine Model of Cerebral Ischemia International Journal of Molecular Sciences, 2022-07-22;23(15):. 2022-07-22 [PMID: 35897671] (Mouse)
• PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury Elife, 2022-07-13;11(0):. 2022-07-13 [PMID: 35822617] (Mouse)
• B Dolfi, A Gallerand, MM Firulyova, Y Xu, J Merlin, A Dumont, A Castiglion, N Vaillant, S Quemener, H Gerke, MI Stunault, PR Schrank, SH Kim, A Zhu, J Ding, J Gilleron, V Magnone, P Barbry, D Dombrowicz, C Duranton, A Wakkach, C Blin-Wakka, B Becher, S Pagnotta, RJ Argüello, P Rantakari, S Chakarov, F Ginhoux, K Zaitsev, KW Kim, L Yvan-Charv, RR Guinamard, JW Williams, S Ivanov Unravelling the sex-specific diversity and functions of adrenal gland macrophages Cell Reports, 2022-06-14;39(11):110949. 2022-06-14 [PMID: 35705045] (Mouse)
• S Kim, W Lee, H Jo, SK Sonn, SJ Jeong, S Seo, J Suh, J Jin, HY Kweon, TK Kim, SH Moon, S Jeon, JW Kim, YR Kim, EW Lee, HK Shin, SH Park, GT Oh The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke Redox Biology, 2022-05-25;54(0):102347. 2022-05-25 [PMID: 35688114] (Mouse)
• H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration Oncogene, 2022-06-09;43(0):267-276. 2022-06-09 [PMID: 35678763] (Mouse)
• A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice Elife, 2022-04-12;11(0):. 2022-04-12 [PMID: 35411847] (Mouse)
• X Li, G He, J Liu, M Yan, M Shen, L Xu, M An, J Huang, Z Gao CCL2-mediated monocytes regulate immune checkpoint blockade resistance in pancreatic cancer International immunopharmacology, 2022-02-17;106(0):108598. 2022-02-17 [PMID: 35183036] (Mouse)
• X Gao, W Li, F Syed, F Yuan, P Li, Q Yu PD-L1 signaling in reactive astrocytes counteracts neuroinflammation and ameliorates neuronal damage after traumatic brain injury Journal of Neuroinflammation, 2022-02-08;19(1):43. 2022-02-08 [PMID: 35135580] (Mouse)
• R Pohl, S Feder, EM Haberl, L Rein-Fisch, TS Weiss, M Spirk, A Bruckmann, N McMullen, CJ Sinal, C Buechler Chemerin Overexpression in the Liver Protects against Inflammation in Experimental Non-Alcoholic Steatohepatitis Biomedicines, 2022-01-07;10(1):. 2022-01-07 [PMID: 35052810] (Mouse)
• HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function JCI Insight, 2022-02-22;0(0):. 2022-02-22 [PMID: 34990413] (Mouse)
• Taito Miyamoto, Ryusuke Murakami, Junzo Hamanishi, Kenji Tanigaki, Yuko Hosoe, Nathan Mise et al. B7-H3 Suppresses Antitumor Immunity via the CCL2–CCR2–M2 Macrophage Axis and Contributes to Ovarian Cancer Progression Cancer Immunology Research 2022-01-01 [PMID: 34799346] (Mouse)
• KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages Nature Communications, 2021-11-17;12(1):6637. 2021-11-17 [PMID: 34789781] (Mouse)
• YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway Acta pharmacologica Sinica, 2021-10-15;0(0):. 2021-10-15 [PMID: 34654875] (Mouse)
• C Luci, E Vieira, M Bourinet, D Rousseau, S Bonnafous, S Patouraux, L Lefevre, F Larbret, V Prod'homme, A Iannelli, A Tran, R Anty, B Bailly-Mai, M Deckert, P Gual SYK-3BP2 pathway activity in parenchymal and myeloid cells is a key pathogenic factor in metabolic steatohepatitis Cellular and Molecular Gastroenterology and Hepatology, 2021-08-16;0(0):. 2021-08-16 [PMID: 34411785] (Mouse)
• F Guo, M Seldin, M Péterfy, S Charugundl, Z Zhou, SD Lee, A Mouton, P Rajbhandar, W Zhang, M Pellegrini, P Tontonoz, AJ Lusis, DM Shih NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice Scientific Reports, 2021-08-12;11(1):16409. 2021-08-12 [PMID: 34385484] (Mouse)
• DJ Levy, A Goundry, RSS Laires, TFR Costa, CM Novo, DJ Grab, JC Mottram, APCA Lima Role of the inhibitor of serine peptidase 2 (ISP2) of Trypanosoma brucei rhodesiense in parasite virulence and modulation of the inflammatory responses of the host PloS Neglected Tropical Diseases, 2021-06-21;15(6):e0009526. 2021-06-21 [PMID: 34153047] (Mouse)
• LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 2021-06-10;12(1):3543. 2021-06-10 [PMID: 34112803] (Mouse)
• MTP de Oliveir, DS Coutinho, SS Guterres, AR Pohlmann, PMRE Silva, MA Martins, A Bernardi Resveratrol-Loaded Lipid-Core Nanocapsules Modulate Acute Lung Inflammation and Oxidative Imbalance Induced by LPS in Mice Pharmaceutics, 2021-05-10;13(5):. 2021-05-10 [PMID: 34068619] (Mouse)
• L Liu, Y Wu, B Wang, Y Jiang, L Lin, X Li, S Yang DA-DRD5 signaling controls colitis by regulating colonic M1/M2 macrophage polarization Cell Death & Disease, 2021-05-17;12(6):500. 2021-05-17 [PMID: 34001860] (Mouse)
• Chunmei Ma, Sheng Li, Yingchao Hu, Yan Ma, Yuqing Wu, Chunyan Wu et al. AIM2 controls microglial inflammation to prevent experimental autoimmune encephalomyelitis Journal of Experimental Medicine 2021-05-03 [PMID: 33710283] (Mouse)
• M Grancieri, HSD Martino, E Gonzalez d Protein Digests and Pure Peptides from Chia Seed Prevented Adipogenesis and Inflammation by Inhibiting PPAR&gamma and NF-&kappaB Pathways in 3T3L-1 Adipocytes Nutrients, 2021-01-08;13(1):. 2021-01-08 [PMID: 33430086] (Mouse)
• E Mai, CM Percopo, AR Limkar, AC Sek, M Ma, HF Rosenberg Respiratory Epithelial Cells Respond to Lactobacillus plantarum but Provide No Cross-Protection against Virus-Induced Inflammation Viruses, 2020-12-22;13(1):. 2020-12-22 [PMID: 33374950] (Mouse)
• M Song, OO Yeku, S Rafiq, T Purdon, X Dong, L Zhu, T Zhang, H Wang, Z Yu, J Mai, H Shen, B Nixon, M Li, RJ Brentjens, X Ma Tumor derived UBR5 promotes ovarian cancer growth and metastasis through inducing immunosuppressive macrophages Nature Communications, 2020-12-08;11(1):6298. 2020-12-08 [PMID: 33293516] (Mouse)
• A Taberner-C, Á Vinué, A Herrero-Ce, M Aguilar-Ba, JT Real, DJ Burks, S Martínez-H, H González-N Dapagliflozin Does Not Modulate Atherosclerosis in Mice with Insulin Resistance International Journal of Molecular Sciences, 2020-12-03;21(23):. 2020-12-03 [PMID: 33287201] (Mouse)
• AM Antonson, MV Evans, JD Galley, HJ Chen, TA Rajasekera, SM Lammers, VL Hale, MT Bailey, TL Gur Unique maternal immune and functional microbial profiles during prenatal stress Sci Rep, 2020-11-20;10(1):20288. 2020-11-20 [PMID: 33219314] (Mouse)
• AS Khan, T Langmann Indole-3-carbinol regulates microglia homeostasis and protects the retina from degeneration J Neuroinflammation, 2020-11-03;17(1):327. 2020-11-03 [PMID: 33143743] (Mouse)
• JR Yaron, L Zhang, Q Guo, EA Awo, M Burgin, LN Schutz, N Zhang, J Kilbourne, J Daggett-Vo, KM Lowe, AR Lucas Recombinant Myxoma Virus-Derived Immune Modulator M-T7 Accelerates Cutaneous Wound Healing and Improves Tissue Remodeling Pharmaceutics, 2020-10-22;12(11):. 2020-10-22 [PMID: 33105865] (Mouse)
• S Ferrara, A Rossi, S Ranucci, I De Fino, A Bragonzi, C Cigana, G Bertoni The Small RNA ErsA Plays a Role in the Regulatory Network of Pseudomonas aeruginosa Pathogenicity in Airway Infections mSphere, 2020-10-14;5(5):. 2020-10-14 [PMID: 33055260] (Mouse)
• T Kawakita, T Kato, T Iwasa, O Erdenebaya, Y Kadota, K Kasai, K Yoshida, M Irahara Mental stress promotes the proliferation of endometriotic lesions in mice Cytokine, 2020-08-06;135(0):155222. 2020-08-06 [PMID: 32768923] (Mouse)
• S Abouelasra, M De Bondt, N Berghmans, M Gouwy, VLS de Oliveir, SC Oliveira, FA Amaral, P Proost, J Van Damme, S Struyf, M De Buck Biological Characterization of Commercial Recombinantly Expressed Immunomodulating Proteins Contaminated with Bacterial Products in the Year 2020: The SAA3 Case Mediators Inflamm., 2020-07-06;2020(0):6087109. 2020-07-06 [PMID: 32694927] (Mouse)
• D Kempuraj, ME Ahmed, GP Selvakumar, R Thangavel, SP Raikwar, SA Zaheer, SS Iyer, C Burton, D James, A Zaheer Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury Mediators Inflamm., 2020-06-24;2020(0):4243953. 2020-06-24 [PMID: 32684835] (Mouse)
• A Jarneborn, M Mohammad, C Engdahl, Z Hu, M Na, A Ali, T Jin Tofacitinib treatment aggravates Staphylococcus aureus septic arthritis, but attenuates sepsis and enterotoxin induced shock in mice Sci Rep, 2020-07-02;10(1):10891. 2020-07-02 [PMID: 32616791] (Mouse)
• A Wolf, M Herb, M Schramm, T Langmann The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye Nat Commun, 2020-06-01;11(1):2709. 2020-06-01 [PMID: 32483169] (Mouse)
• M Mohammad, Z Hu, A Ali, PK Kopparapu, M Na, A Jarneborn, MDN Stroparo, MT Nguyen, A Karlsson, F Götz, R Pullerits, T Jin The role of Staphylococcus aureus lipoproteins in hematogenous septic arthritis Sci Rep, 2020-05-13;10(1):7936. 2020-05-13 [PMID: 32404866] (Mouse)
• M Rahabi, G Jacquemin, M Prat, E Meunier, M AlaEddine, B Bertrand, L Lefèvre, K Benmoussa, P Batigne, A Aubouy, J Auwerx, S Kirzin, D Bonnet, M Danjoux, B Pipy, L Alric, H Authier, A Coste Divergent Roles for Macrophage C-type Lectin Receptors, Dectin-1 and Mannose Receptors, in the Intestinal Inflammatory Response Cell Rep, 2020-03-31;30(13):4386-4398.e5. 2020-03-31 [PMID: 32234475] (Mouse)
• V Garcia-Cas, G Marcial, L Albarracín, M Tomokiyo, P Clua, H Takahashi, H Kitazawa, A Garcia-Can, J Villena The Exopolysaccharide of Lactobacillus fermentum UCO-979C Is Partially Involved in Its Immunomodulatory Effect and Its Ability to Improve the Resistance against Helicobacter pylori Infection Microorganisms, 2020-03-27;8(4):. 2020-03-27 [PMID: 32230910] (Mouse)
• MB Reis, J Elias-Oliv, MR Pastore, SG Ramos, LG Gardinassi, LH Faccioli Interleukin-1 Receptor-Induced Nitric Oxide Production in the Pancreas Controls Hyperglycemia Caused by Scorpion Envenomation Toxins (Basel), 2020-03-05;12(3):. 2020-03-05 [PMID: 32150895] (Mouse)
• RDC da Cunha d, MM Cruz, TM de Farias, VS da Silva, J de Jesus S, MM Telles, MIC Alonso-Val Fish oil reverses metabolic syndrome, adipocyte dysfunction, and altered adipokines secretion triggered by high-fat diet-induced obesity Physiol Rep, 2020-02-01;8(4):e14380. 2020-02-01 [PMID: 32109344] (Mouse)
• Y Lu, J Ma, J Zhao, Z Song, C Zhou, X Liu, W Teng, W Wang, Q Zhang, W Yan, P Jiao The Role of MKP-5 in Adipocyte-Macrophage Interactions during Obesity Obes Facts, 2020-01-21;0(0):1-16. 2020-01-21 [PMID: 31962332] (Mouse)
• O Danov, L Lasswitz, H Obernolte, C Hesse, A Braun, S Wronski, K Sewald Rupintrivir reduces RV-induced TH-2 cytokine IL-4 in precision-cut lung slices (PCLS) of HDM-sensitized mice ex vivo Respir. Res., 2019-10-22;20(1):228. 2019-10-22 [PMID: 31640701] (Mouse)
• SS Welc, I Flores, M Wehling-He, J Ramos, Y Wang, C Bertoni, JG Tidball Targeting a therapeutic LIF transgene to muscle via the immune system ameliorates muscular dystrophy Nat Commun, 2019-06-26;10(1):2788. 2019-06-26 [PMID: 31243277] (Mouse, Transgenic Mouse)
• BE Hsu, S Tabariès, RM Johnson, S Andrzejews, J Senecal, C Lehuédé, MG Annis, EH Ma, S Völs, L Ramsay, R Froment, A Monast, IR Watson, Z Granot, RG Jones, J St-Pierre, PM Siegel Immature Low-Density Neutrophils Exhibit Metabolic Flexibility that Facilitates Breast Cancer Liver Metastasis Cell Rep, 2019-06-25;27(13):3902-3915.e6. 2019-06-25 [PMID: 31242422] (Mouse)
• M Mohammad, MT Nguyen, C Engdahl, M Na, A Jarneborn, Z Hu, A Karlsson, R Pullerits, A Ali, F Götz, T Jin The YIN and YANG of lipoproteins in developing and preventing infectious arthritis by Staphylococcus aureus PLoS Pathog., 2019-06-21;15(6):e1007877. 2019-06-21 [PMID: 31226163] (Mouse)
• M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy Nat Commun, 2019-06-11;10(1):2416. 2019-06-11 [PMID: 31186412] (Mouse)
• V Maximov, Z Chen, Y Wei, MH Robinson, CJ Herting, NS Shanmugam, VA Rudneva, KC Goldsmith, TJ MacDonald, PA Northcott, D Hambardzum, AM Kenney Tumour-associated macrophages exhibit anti-tumoural properties in Sonic Hedgehog medulloblastoma Nat Commun, 2019-06-03;10(1):2410. 2019-06-03 [PMID: 31160587] (Mouse)
• VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy EBioMedicine, 2019-05-23;0(0):. 2019-05-23 [PMID: 31130472] (Mouse)
• M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice J Neuroinflammation, 2019-04-02;16(1):69. 2019-04-02 [PMID: 30940161] (Mouse)
• AML Scantleber, M Uil, LM Butter, R Poelman, N Claessen, SE Girardin, S Florquin, JJTH Roelofs, JC Leemans NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin PLoS ONE, 2019-03-25;14(3):e0214437. 2019-03-25 [PMID: 30908533] (Mouse)
• AS Ernst, LI Böhler, AM Hagenston, A Hoffmann, S Heiland, C Sticht, M Bendszus, M Hecker, H Bading, HH Marti, T Korff, R Kunze EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke Acta Neuropathol Commun, 2019-02-05;7(1):15. 2019-02-05 [PMID: 30722785] (Mouse)
• Y Pan, X Hui, RLC Hoo, D Ye, CYC Chan, T Feng, Y Wang, KSL Lam, A Xu Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation J. Clin. Invest., 2019-01-22;129(2):834-849. 2019-01-22 [PMID: 30667374] (Mouse)
• CC Campa, RL Silva, JP Margaria, T Pirali, MS Mattos, LR Kraemer, DC Reis, G Grosa, F Copperi, EM Dalmarco, RCP Lima-Júnio, S Aprile, V Sala, F Dal Bello, DS Prado, JC Alves-Filh, C Medana, GD Cassali, GC Tron, MM Teixeira, E Ciraolo, RC Russo, E Hirsch Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis Nat Commun, 2018-12-12;9(1):5232. 2018-12-12 [PMID: 30542075] (Mouse)
• GM Wiedemann, C Aithal, A Kraechan, C Heise, BL Cadilha, J Zhang, P Duewell, R Ballotti, S Endres, C Bertolotto, S Kobold Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma Transl Oncol, 2018-11-28;12(2):350-360. 2018-11-28 [PMID: 30502589] (Mouse)
• SJ Gurczynski, N Nathani, HI Warheit-Ni, EM Hult, A Podsiad, J Deng, RL Zemans, U Bhan, BB Moore CCR2 mediates increased susceptibility to post-H1N1 bacterial pneumonia by limiting dendritic cell induction of IL-17 Mucosal Immunol, 2018-11-29;0(0):. 2018-11-29 [PMID: 30498200] (Mouse)
• M Talbot, M Hamel-Auge, MJ Beaulieu, M Gazzola, A Lechasseur, S Aubin, MÈ Paré, D Marsolais, Y Bossé, MC Morissette Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice Respir. Res., 2018-07-03;19(1):131. 2018-07-03 [PMID: 29970083] (Mouse)
• DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms Mol. Psychiatry, 2018-06-06;24(10):1533-1548. 2018-06-06 [PMID: 29875474] (Mouse)
• A Porrello, PL Leslie, EB Harrison, BK Gorentla, S Kattula, SK Ghosh, SH Azam, A Holtzhause, YL Chao, MC Hayward, TA Waugh, S Bae, V Godfrey, SH Randell, C Oderup, L Makowski, J Weiss, MD Wilkerson, DN Hayes, HS Earp, AS Baldwin, AS Wolberg, CV Pecot Factor XIIIA-expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking Nat Commun, 2018-05-18;9(1):1988. 2018-05-18 [PMID: 29777108] (Mouse)
• KJ Katschke, H Xi, C Cox, T Truong, Y Malato, WP Lee, B McKenzie, R Arceo, J Tao, L Rangell, M Reichelt, L Diehl, J Elstrott, RM Weimer, MVL Campagne Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy Sci Rep, 2018-05-09;8(1):7348. 2018-05-09 [PMID: 29743491] (Mouse)
• F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop Glia, 2018-04-17;0(0):. 2018-04-17 [PMID: 29665074] (Mouse)
• IK Sundar, K Rashid, J Gerloff, J Rangel-Mor, D Li, I Rahman Genetic ablation of histone deacetylase 2 leads to lung cellular senescence and lymphoid follicle formation in COPD/emphysema FASEB J., 2018-04-09;0(0):fj201701518R. 2018-04-09 [PMID: 29630406] (Mouse)
• A Sagiv, A Bar-Shai, N Levi, M Hatzav, L Zada, Y Ovadya, L Roitman, G Manella, O Regev, J Majewska, E Vadai, R Eilam, SW Feigelson, M Tsoory, M Tauc, R Alon, V Krizhanovs p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence Cell Rep, 2018-03-27;22(13):3468-3479. 2018-03-27 [PMID: 29590616] (Mouse)
• D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair Front Immunol, 2018-03-05;9(0):417. 2018-03-05 [PMID: 29556234] (Mouse)
• Z Li, J Zhao, S Zhang, SA Weinman FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation Cell Death Discov, 2018-02-13;4(0):16. 2018-02-13 [PMID: 29531813] (Mouse)
• V Besnard, R Dagher, T Madjer, A Joannes, M Jaillet, M Kolb, P Bonniaud, LA Murray, MA Sleeman, B Crestani Identification of periplakin as a major regulator of lung injury and repair in mice JCI Insight, 2018-03-08;3(5):. 2018-03-08 [PMID: 29515024] (Mouse)
• M Ma, JL Redes, CM Percopo, KM Druey, HF Rosenberg Alternaria alternata challenge at the nasal mucosa results in eosinophilic inflammation and increased susceptibility to influenza virus infection Clin. Exp. Allergy, 2018-04-15;0(0):. 2018-04-15 [PMID: 29473965] (Mouse)
• B Bergmann, P Jirholt, P Henning, C Lindholm, C Ohlsson, IB McInnes, UH Lerner, I Gjertsson Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction ininduced arthritis Infect. Immun., 2018-04-23;0(0):. 2018-04-23 [PMID: 29440371] (Mouse)
• EE Hornick, B Banoth, AM Miller, ZR Zacharias, N Jain, ME Wilson, KN Gibson-Cor, KL Legge, GA Bishop, FS Sutterwala, SL Cassel Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection J. Immunol., 2017-12-27;0(0):. 2017-12-27 [PMID: 29282312] (Mouse)
• L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration J. Biol. Chem., 2017-06-27;0(0):. 2017-06-27 [PMID: 28655763] (Mouse)
• G Stokman, L Kors, PJ Bakker, E Rampanelli, N Claessen, GJD Teske, L Butter, H van Andel, MA van den Be, PWB Larsen, MC Dessing, CJ Zuurbier, SE Girardin, S Florquin, JC Leemans NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity J. Exp. Med., 2017-06-16;0(0):. 2017-06-16 [PMID: 28626071] (Mouse)
• Á Vinué, J Navarro, A Herrero-Ce, M García-Cub, I Andrés-Bla, S Martínez-H, JT Real, JF Ascaso, H González-N The GLP-1 analogue lixisenatide decreases atherosclerosis in insulin-resistant mice by modulating macrophage phenotype Diabetologia, 2017-06-12;0(0):. 2017-06-12 [PMID: 28608285] (Mouse)
• JM Orellana, K Kampe, F Schulze, J Sieber, AW Jehle Fetuin-A aggravates lipotoxicity in podocytes via interleukin-1 signaling Physiol Rep, 2017-05-01;5(10):. 2017-05-01 [PMID: 28554965] (Mouse)
• CT Molloy, JS Andonian, HM Seltzer, MC Procario, ME Watson, JB Weinberg Contributions of CD8 T cells to the pathogenesis of mouse adenovirus type 1 respiratory infection Virology, 2017-04-11;507(0):64-74. 2017-04-11 [PMID: 28410483] (Mouse)
• M Lynch, TA Walsh, I Marszalows, AE Webb, M MacAogain, TR Rogers, H Windle, D Kelleher, MJ O'Connell, CE Loscher Surface layer proteins from virulent Clostridium difficile ribotypes exhibit signatures of positive selection with consequences for innate immune response BMC Evol. Biol, 2017-03-23;17(1):90. 2017-03-23 [PMID: 28335725] (Mouse)
• LT Hsieh, MV Nastase, H Roedig, J Zeng-Brouw, C Poluzzi, S Schwalm, C Fork, C Tredup, RP Brandes, M Wygrecka, A Huwiler, J Pfeilschif, L Schaefer Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants Int J Mol Sci, 2017-03-09;18(3):. 2017-03-09 [PMID: 28282921] (Mouse)
• M Na, W Wang, Y Fei, E Josefsson, A Ali, T Jin Both anti-TNF and CTLA4 Ig treatments attenuate the disease severity of staphylococcal dermatitis in mice PLoS ONE, 2017-03-06;12(3):e0173492. 2017-03-06 [PMID: 28264025] (Mouse)
• A Kawaguchi, T Suzuki, Y Ohara, K Takahashi, Y Sato, A Ainai, N Nagata, M Tashiro, H Hasegawa Impacts of allergic airway inflammation on lung pathology in a mouse model of influenza A virus infection PLoS ONE, 2017-02-28;12(2):e0173008. 2017-02-28 [PMID: 28245238] (Mouse)
• YT Chu, SW Wan, YC Chang, CK Lee, BA Wu-Hsieh, R Anderson, YS Lin Antibodies against nonstructural protein 1 protect mice from dengue virus-induced mast cell activation Lab. Invest, 2017-02-27;0(0):. 2017-02-27 [PMID: 28240747] (Mouse)
• T Hartwig, A Montinaro, S von Karste, A Sevko, S Surinova, A Chakravart, L Taraborrel, P Draber, E Lafont, F Arce Varga, MA El-Bahrawy, SA Quezada, H Walczak The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2 Mol. Cell, 2017-02-16;65(4):730-742.e5. 2017-02-16 [PMID: 28212753] (Mouse)
• Xue Jiang APPL1 prevents pancreatic beta cell death and inflammation by dampening NF?B activation in a mouse model of type 1 diabetes Diabetologia, 2016-12-23;0(0):. 2016-12-23 [PMID: 28011992] (Mouse)
• Andrey Lozhkin NADPH oxidase 4 regulates vascular inflammation in aging and atherosclerosis J. Mol. Cell. Cardiol, 2016-12-14;0(0):. 2016-12-14 [PMID: 27986445] (Mouse)
• Bryan Simons PGI2 Controls Pulmonary NK Cells That Prevent Airway Sensitization to House Dust Mite Allergen J. Immunol, 2016-11-28;0(0):. 2016-11-28 [PMID: 27895167] (Mouse)
• Sundar , Isaac K, Ahmad , Tanveer, Yao , Hongwei, Hwang , Jae-woon, Gerloff , Janice, Lawrence , B Paige, Sellix , Michael, Rahman , Irfan Influenza A virus-dependent remodeling of pulmonary clock function in a mouse model of COPD. Sci Rep, 2015-04-29;4(0):9927. 2015-04-29 [PMID: 25923474] (Mouse)
• Goritzka M, Makris S, Kausar F, Durant L, Pereira C, Kumagai Y, Culley F, Mack M, Akira S, Johansson C Alveolar macrophage-derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes. J Exp Med, 2015-04-20;212(5):699-714. 2015-04-20 [PMID: 25897172] (Mouse)
• Dau T, Sarker R, Yildirim A, Eickelberg O, Jenne D Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nat Commun, 2015-04-10;6(0):6722. 2015-04-10 [PMID: 25857284] (Mouse)
• Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages. J Immunol, 2015-02-27;194(7):3156-68. 2015-02-27 [PMID: 25725107] (Mouse)
• Larson-Casey J, Murthy S, Ryan A, Carter A Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. J Biol Chem, 2014-11-05;289(52):36204-19. 2014-11-05 [PMID: 25378391] (Mouse)
• Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Nature, 2014-10-22;515(7525):130-3. 2014-10-22 [PMID: 25337873] (Mouse)
• Mancuso P, O Brien E, Prano J, Goel D, Aronoff D No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice. PLoS ONE, 2014-09-09;9(9):e106420. 2014-09-09 [PMID: 25203099] (Mouse)
• Walsh K, Teijaro J, Brock L, Fremgen D, Collins P, Rosen H, Oldstone M Animal model of respiratory syncytial virus: CD8+ T cells cause a cytokine storm that is chemically tractable by sphingosine-1-phosphate 1 receptor agonist therapy. J Virol, 2014-03-26;88(11):6281-93. 2014-03-26 [PMID: 24672024] (Mouse)
• Liu , Xianglan, McMurphy , Travis, Xiao , Run, Slater , Andrew, Huang , Wei, Cao , Lei Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice. Mol Ther, 2014-03-18;22(7):1275-84. 2014-03-18 [PMID: 24637454] (Mouse)
• Teijaro J, Walsh K, Rice S, Rosen H, Oldstone M Mapping the innate signaling cascade essential for cytokine storm during influenza virus infection. Proc Natl Acad Sci U S A, 2014-02-26;111(10):3799-804. 2014-02-26 [PMID: 24572573] (Mouse)
• Hernandes M, D'Avila J, Trevelin S, Reis P, Kinjo E, Lopes L, Castro-Faria-Neto H, Cunha F, Britto L, Bozza F The role of Nox2-derived ROS in the development of cognitive impairment after sepsis. J Neuroinflammation, 2014-02-27;11(0):36. 2014-02-27 [PMID: 24571599] (Mouse)
• Paradis M, Mindt B, Duerr C, Rojas O, Ng D, Boulianne B, McCarthy D, Yu M, Summers deLuca L, Ward L, Waldron J, Philpott D, Gommerman J, Fritz J A TNF-alpha-CCL20-CCR6 axis regulates Nod1-induced B cell responses. J Immunol, 2014-02-17;192(6):2787-99. 2014-02-17 [PMID: 24534531] (Mouse)
• Tilstam P, Gijbels M, Habbeddine M, Cudejko C, Asare Y, Theelen W, Zhou B, Doring Y, Drechsler M, Pawig L, Simsekyilmaz S, Koenen R, de Winther M, Lawrence T, Bernhagen J, Zernecke A, Weber C, Noels H Bone marrow-specific knock-in of a non-activatable Ikkalpha kinase mutant influences haematopoiesis but not atherosclerosis in Apoe-deficient mice. PLoS ONE, 2014-02-03;9(2):e87452. 2014-02-03 [PMID: 24498325] (Mouse)
• Malmhall C, Alawieh S, Lu Y, Sjostrand M, Bossios A, Eldh M, Radinger M MicroRNA-155 is essential for T(H)2-mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immunol, 2013-12-24;133(5):1429-38, 1438. 2013-12-24 [PMID: 24373357] (Mouse)
• Brochetta C, Suzuki R, Vita F, Soranzo M, Claver J, Madjene L, Attout T, Vitte J, Varin-Blank N, Zabucchi G, Rivera J, Blank U Munc18-2 and syntaxin 3 control distinct essential steps in mast cell degranulation. J Immunol, 2013-12-09;192(1):41-51. 2013-12-09 [PMID: 24323579] (Rat)
• Everitt , Aaron R, Clare , Simon, McDonald , Jacqueli, Kane , Leanne, Harcourt , Katherin, Ahras , Malika, Lall , Amar, Hale , Christin, Rodgers , Angela, Young , Douglas, Haque , Ashraful, Billker , Oliver, Tregoning , John S, Dougan , Gordon, Kellam , Paul Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model. PLoS ONE, 2013-11-21;8(11):e80723. 2013-11-21 [PMID: 24278312] (Mouse)
• Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation. Diabetes, 2013-11-05;63(3):850-66. 2013-11-05 [PMID: 24194503] (Mouse)
• Hwang J, Sundar I, Yao H, Sellix M, Rahman I Circadian clock function is disrupted by environmental tobacco/cigarette smoke, leading to lung inflammation and injury via a SIRT1-BMAL1 pathway. FASEB J, 2013-09-11;28(1):176-94. 2013-09-11 [PMID: 24025728] (Mouse)
• Gauvreau D, Gupta A, Fisette A, Tom F, Cianflone K Deficiency of C5L2 increases macrophage infiltration and alters adipose tissue function in mice. PLoS ONE, 2013-04-22;8(4):e60795. 2013-04-22 [PMID: 23630572] (Mouse)
• Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes. EMBO Mol Med, 2013-04-01;5(4):516-30. 2013-04-01 [PMID: 23554169] (Mouse)
• Wu Z, MacNeil A, Berman J, Lin T Syntaxin binding protein 1 is not required for allergic inflammation via IgE-mediated mast cell activation. PLoS ONE, 2013-03-06;8(3):e58560. 2013-03-06 [PMID: 23484036] (Mouse)
• Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice. PLoS ONE, 2013-02-13;8(2):e56866. 2013-02-13 [PMID: 23418608] (Mouse)
• Miegueu P, Cianflone K, Richard D, St-Pierre D Effect of secretin on preadipocyte, differentiating and mature adipocyte functions. Int J Obes (Lond), 2012-05-08;37(3):366-74. 2012-05-08 [PMID: 22565418] (Mouse)
• Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection. Infect. Immun., 2011-10-24;80(1):100-9. 2011-10-24 [PMID: 22025515] (Mouse)
• Walsh KB, Teijaro JR, Wilker PR Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus. Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23. 2011-06-29 [PMID: 21715659] (Mouse)
• McMillan DH, Baglole CJ, Thatcher TH, Maggirwar S, Sime PJ, Phipps RP Lung-targeted overexpression of the NF-kappaB member RelB inhibits cigarette smoke-induced inflammation. Am. J. Pathol., 2011-05-05;179(1):125-33. 2011-05-05 [PMID: 21703398] (Mouse)
• Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa. J. Immunol., 2011-03-25;186(9):5425-34. 2011-03-25 [PMID: 21441447] (Mouse)
• Russo RC, Garcia CC, Barcelos LS, Rachid MA, Guabiraba R, Roffe E, Souza AL, Sousa LP, Mirolo M, Doni A, Cassali GD, Pinho V, Locati M, Teixeira MM Phosphoinositide 3-kinase gamma plays a critical role in bleomycin-induced pulmonary inflammation and fibrosis in mice. J. Leukoc. Biol., 2010-11-02;89(2):269-82. 2010-11-02 [PMID: 21048214] (Mouse)
• van Neerven S, Regen T, Wolf D, Nemes A, Johann S, Beyer C, Hanisch UK, Mey J Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. J. Neurochem., 2010-06-16;114(5):1511-26. 2010-06-16 [PMID: 20557428] (Mouse)
• Vannella KM, Luckhardt TR, Wilke CA, van Dyk LF, Toews GB, Moore BB Latent herpesvirus infection augments experimental pulmonary fibrosis. Am. J. Respir. Crit. Care Med., 2009-12-10;181(5):465-77. 2009-12-10 [PMID: 20185751] (Mouse)
• Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection. J. Immunol., 2009-07-27;183(4):2642-9. 2009-07-27 [PMID: 19635910] (Mouse)
• Li Z, Alam S, Wang J, Sandstrom CS, Janciauskiene S, Mahadeva R Oxidized alpha1-antitrypsin stimulates the release of monocyte chemotactic protein-1 from lung epithelial cells: potential role in emphysema. Am. J. Physiol. Lung Cell Mol. Physiol., 2009-06-12;297(2):L388-400. 2009-06-12 [PMID: 19525388] (Mouse)
• Lukkarinen H, Hogmalm A, Lappalainen U, Bry K Matrix metalloproteinase-9 deficiency worsens lung injury in a model of bronchopulmonary dysplasia. Am. J. Respir. Cell Mol. Biol., 2008-12-18;41(1):59-68. 2008-12-18 [PMID: 19097983] (Mouse)
• Christophi GP, Hudson CA, Panos M, Gruber RC, Massa PT Modulation of macrophage infiltration and inflammatory activity by the phosphatase SHP-1 in virus-induced demyelinating disease. J. Virol., 2008-11-05;83(2):522-39. 2008-11-05 [PMID: 18987138] (Mouse)
• Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse. Atherosclerosis, 2008-09-02;204(1):147-55. 2008-09-02 [PMID: 18842266] (Mouse)
• Sun J, Ramnath RD, Tamizhselvi R, Bhatia M Neurokinin A engages neurokinin-1 receptor to induce NF-kappaB-dependent gene expression in murine macrophages: implications of ERK1/2 and PI 3-kinase/Akt pathways. Am. J. Physiol., Cell Physiol., 2008-07-02;295(3):C679-91. 2008-07-02 [PMID: 18596216] (Mouse)
• Munitz A, Brandt EB, Mingler M, Finkelman FD, Rothenberg ME Distinct roles for IL-13 and IL-4 via IL-13 receptor alpha1 and the type II IL-4 receptor in asthma pathogenesis. Proc. Natl. Acad. Sci. U.S.A., 2008-05-14;105(20):7240-5. 2008-05-14 [PMID: 18480254] (Mouse)
• Chou SY, Weng JY, Lai HL, Liao F, Sun SH, Tu PH, Dickson DW, Chern Y Expanded-polyglutamine huntingtin protein suppresses the secretion and production of a chemokine (CCL5/RANTES) by astrocytes. J. Neurosci., 2008-03-26;28(13):3277-90. 2008-03-26 [PMID: 18367595] (Mouse)
• Brandt EB, Mingler MK, Stevenson MD, Wang N, Khurana Hershey GK, Whitsett JA, Rothenberg ME Surfactant protein D alters allergic lung responses in mice and human subjects. J. Allergy Clin. Immunol., 2008-03-19;121(5):1140-1147.e2. 2008-03-19 [PMID: 18355911] (Mouse)
• Cardona AE, Sasse ME, Liu L, Cardona SM, Mizutani M, Savarin C, Hu T, Ransohoff RM Scavenging roles of chemokine receptors: chemokine receptor deficiency is associated with increased levels of ligand in circulation and tissues. Blood, 2008-03-17;112(2):256-63. 2008-03-17 [PMID: 18347198] (Mouse)
• Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J. Immunol., 2008-01-15;180(2):1080-7. 2008-01-15 [PMID: 18178848] (Mouse)
• Arias MA, Jaramillo G, Lopez YP, Mejia N, Mejia C, Pantoja AE, Shattock RJ, Garcia LF, Griffin GE Mycobacterium tuberculosis antigens specifically modulate CCR2 and MCP-1/CCL2 on lymphoid cells from human pulmonary hilar lymph nodes. J. Immunol., 2007-12-15;179(12):8381-91. 2007-12-15 [PMID: 18056384] (Human)
• Wang KX, Shi Y, Denhardt DT Osteopontin regulates hindlimb-unloading-induced lymphoid organ atrophy and weight loss by modulating corticosteroid production. Proc. Natl. Acad. Sci. U.S.A., 2007-09-04;104(37):14777-82. 2007-09-04 [PMID: 17785423] (Mouse)
• Hegde A, Zhang H, Moochhala SM, Bhatia M Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. J. Leukoc. Biol., 2007-06-12;82(3):678-85. 2007-06-12 [PMID: 17565047] (Mouse)
• Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J. Immunol., 2007-06-15;178(12):8090-6. 2007-06-15 [PMID: 17548647] (Mouse)
• Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity, 2007-04-12;26(4):445-59. 2007-04-12 [PMID: 17433730] (Mouse)
• Shiratsuchi Y, Iyoda T, Tanimoto N, Kegai D, Nagata K, Kobayashi Y Infiltrating neutrophils induce allospecific CTL in response to immunization with apoptotic cells via MCP-1 production. J. Leukoc. Biol., 2006-11-09;81(2):412-20. 2006-11-09 [PMID: 17095610] (Mouse)
• Conrad SM, Strauss-Ayali D, Field AE, Mack M, Mosser DM Leishmania-derived murine monocyte chemoattractant protein 1 enhances the recruitment of a restrictive population of CC chemokine receptor 2-positive macrophages. Infect. Immun., 2006-11-06;75(2):653-65. 2006-11-06 [PMID: 17088347] (Parasite - Leishmania)
• Lin TY, London CA A functional comparison of canine and murine bone marrow derived cultured mast cells. Vet. Immunol. Immunopathol., 2006-10-06;114(3):320-34. 2006-10-06 [PMID: 17027994] (Mouse)
• Gomes RN, Bozza FA, Amancio RT, Japiassu AM, Vianna RC, Larangeira AP, Gouvea JM, Bastos MS, Zimmerman GA, Stafforini DM, Prescott SM, Bozza PT, Castro-Faria-Neto HC Exogenous platelet-activating factor acetylhydrolase reduces mortality in mice with systemic inflammatory response syndrome and sepsis. Shock, 2006-07-01;26(1):41-9. 2006-07-01 [PMID: 16783197] (Mouse)
• Rodriguez N, Wantia N, Fend F, Durr S, Wagner H, Miethke T Differential involvement of TLR2 and TLR4 in host survival during pulmonary infection with Chlamydia pneumoniae. Eur. J. Immunol., 2006-05-01;36(5):1145-55. 2006-05-01 [PMID: 16609927] (Mouse)
• Lu FL, Johnston RA, Flynt L, Theman TA, Terry RD, Schwartzman IN, Lee A, Shore SA Increased pulmonary responses to acute ozone exposure in obese db/db mice. Am. J. Physiol. Lung Cell Mol. Physiol., 2005-12-22;290(5):L856-65. 2005-12-22 [PMID: 16373670] (Mouse)
• Carpenter KJ, Hogaboam CM Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis. Infect. Immun., 2005-11-01;73(11):7198-207. 2005-11-01 [PMID: 16239514] (Mouse)
• Barcelos LS, Talvani A, Teixeira AS, Vieira LQ, Cassali GD, Andrade SP, Teixeira MM Impaired inflammatory angiogenesis, but not leukocyte influx, in mice lacking TNFR1. J. Leukoc. Biol., 2005-05-13;78(2):352-8. 2005-05-13 [PMID: 15894588] (Mouse)

FAQs for CCL2/JE/MCP-1 (DY479). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: Ccl2