Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Ccl2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using DY479.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse CCL2/JE/MCP-1 DuoSet ELISA, 15 Plate

  • C-C motif chemokine ligand 2
  • CCL2
  • GDCF-2
  • HC11
  • HSMCR30
  • MCAF
  • Mcp1
  • MCP-1
  • SCYA2
  • SMC-CF

Background

CCL2/JE/MCP-1, is a chemokine that binds the receptor CCR2 and induces the chemoattraction of mononuclear cells. It induces the activation of monocytes, NK cells, lymphocytes, and basophils. Additionally, CCL2 promotes Th2 polarization in CD4+ T cells, and CCL2-mediated recruitment of monocytes to sites of inflammation contributes to disease severity in atherosclerosis, multiple sclerosis, and allergic asthma. Endogenous proteolytic trimming of CCL2 at the N-terminus, including the N-terminal pyrrolidone carboxylic acid-modified glutamine, downregulates activity but not receptor binding.

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Publications for CCL2/JE/MCP-1 (DY479)(169)

We have publications tested in 5 confirmed species: Human, Mouse, Rat, Parasite - Leishmania, Transgenic Mouse.


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Human
(1)
Mouse
(165)
Rat
(1)
Parasite - Leishmania
(1)
Transgenic Mouse
(5)
All Species
Showing Publications 1 - 10 of 169. Show All 169 Publications.
Publications using DY479 Applications Species
Hamadi, N;Al?Salam, S;Beegam, S;Zaaba, N;Elzaki, O;Nemmar, A; Chronic Exposure to Two Regimens of Waterpipe Smoke Elicits Lung Injury, Genotoxicity, and Mitochondrial Impairment with the Involvement of MAPKs Activation in Mice International journal of molecular sciences 2025-01-06 [PMID: 39796284] (Mouse) Mouse
Pinto, LG;Vilar, B;McNaughton, PA; PGE2 and HCN2 ion channels are critical mediators of pain initiated by angiotensin II Brain, behavior, and immunity 2024-12-28 [PMID: 39736364] (Mouse) Mouse
Cheung, EC;Strathdee, D;Stevenson, D;Coomes, J;Blyth, K;Vousden, KH; Regulation of ROS signaling by TIGAR induces cancer-modulating responses in the tumor microenvironment Proceedings of the National Academy of Sciences of the United States of America 2024-12-10 [PMID: 39636862] (Mouse) Mouse
Guo, ZF;Tongmuang, N;Li, C;Zhang, C;Hu, L;Capreri, D;Zuo, MX;Summer, R;Sun, J; Inhibiting endothelial cell Mst1 attenuates acute lung injury in mice JCI insight 2024-09-10 [PMID: 39253972] (Mouse, Transgenic Mouse) Mouse, Transgenic Mouse
Nayer, B;Tan, JL;Alshoubaki, YK;Lu, YZ;Legrand, JMD;Lau, S;Hu, N;Park, AJ;Wang, XN;Amann-Zalcenstein, D;Hickey, PF;Wilson, T;Kuhn, GA;Müller, R;Vasanthakumar, A;Akira, S;Martino, MM; Local administration of regulatory T cells promotes tissue healing Nature communications 2024-09-09 [PMID: 39251592] (Mouse) Mouse
Gabele, L;Bochow, I;Rieke, N;Sieben, C;Michaelsen-Preusse, K;Hosseini, S;Korte, M; H7N7 viral infection elicits pronounced, sex-specific neuroinflammatory responses in vitro Frontiers in cellular neuroscience 2024-08-07 [PMID: 39171200] (Mouse) Mouse
Galley, JD;King, MK;Rajasekera, TA;Batabyal, A;Woodke, ST;Gur, TL; Gestational administration of Bifidobacterium dentium results in intergenerational modulation of inflammatory, metabolic, and social behavior Brain, behavior, and immunity 2024-08-12 [PMID: 39128569] (Mouse) Mouse
Sun, L;Apweiler, M;Tirkey, A;Klett, D;Normann, C;Dietz, GPH;Lehner, MD;Fiebich, BL; Anti-Neuroinflammatory Effects of Ginkgo biloba Extract EGb 761 in LPS-Activated BV2 Microglial Cells International journal of molecular sciences 2024-07-25 [PMID: 39125680] (Mouse) Mouse
Lai, HC;Chen, PH;Tang, CH;Chen, LW; IL-10 Enhances the Inhibitory Effect of Adipose-Derived Stromal Cells on Insulin Resistance/Liver Gluconeogenesis by Treg Cell Induction International journal of molecular sciences 2024-07-25 [PMID: 39125659] (Mouse) Mouse
Huang, Q;Yang, G;Tang, C;Dou, B;Hu, Y;Liu, H;Wu, X;Zhang, H;Wang, H;Xu, L;Yang, XD;Xu, Y;Zheng, Y; Rujin Jiedu decoction protects against influenza virus infection by modulating gut microbiota Heliyon 2024-07-15 [PMID: 39071618] (Mouse) Mouse
Show All 169 Publications.

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Bioinformatics

Gene Symbol Ccl2