MMP‑24 was detected in immersion fixed paraffin-embedded sections of human brain using Rabbit Anti-Human/Mouse MMP-24/MT5-MMP Polyclonal Antibody (Catalog # AB924) at 15 µg/mL overnight at 4 °C. Tissue was stained ...read more
MMP‑24 was detected in immersion fixed paraffin-embedded sections of human brain (astrocytoma) using Rabbit Anti-Human/Mouse MMP‑24/MT5-MMP Polyclonal Antibody (Catalog # AB924) at 15 µg/mL overnight at 4 °C. ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Protein A or G purified
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for MMP-24/MT5-MMP Antibody
matrix metallopeptidase 24 (membrane-inserted)
matrix metalloproteinase 24 (membrane-inserted)
membrane-type 5 matrix metalloproteinase
Membrane-type matrix metalloproteinase 5
Membrane-type-5 matrix metalloproteinase
The matrix metalloproteinases (MMPs) consist of 24 known human zinc proteases with essential roles in breaking down components of the extracellular matrix (ECM). Additional MMP substrates include cytokines, chemokines, growth factors and binding proteins, cell/cell adhesion molecules, and other proteinases. With a few exceptions, MMPs share common structural motifs including a pro-peptide domain, a catalytic domain, a hinge region, and a hemopexin-like domain. Synthesized as pro-enzymes, most MMPs are secreted before conversion to their active form. MMP activities are modulated on several levels including transcription, pro-enzyme activation, or by their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs). A subset of MMPs are associated with membranes and designated as membrane-type metalloproteinases (MT-MMP).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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