MMP-10 Antibody (MM0024-9G10) - Azide and BSA Free

Immunohistochemistry-Paraffin: MMP10 Antibody (MM0019-9G10) [NB110-60990] - Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: MM0024-9G10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

MMP-10 Antibody (MM0024-9G10) - Azide and BSA Free Summary

• Immunogen: Human recombinant MMP-10
• Specificity: This antibody recognizes human MMP-10 in western blot without cross reactivity other human MMPs.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: MMP10
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:300
  • Western Blot 1:1000

Reactivity Notes

This antibody is reactive against human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Alternate Names for MMP-10 Antibody (MM0024-9G10) - Azide and BSA Free

• EC 3.4.24
• EC 3.4.24.22
• matrix metallopeptidase 10 (stromelysin 2)
• matrix metalloprotease 10
• matrix metalloproteinase 10 (stromelysin 2)
• Matrix metalloproteinase-10
• MMP10
• MMP-10
• SL-2
• STMY2stromelysin-2
• Stromelysin 2
• transin 2
• transin-2

Background

Proteins of the matrix metalloproteinase (MMP) family are zinc containing proteolytic enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They also play an important role in apoptosis, tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Most of the MMP's contain a common domain structure, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 degrades proteoglycans, gelatins of type I, III, IV, and V; weakly collagens III, IV, and V. and fibronectin. It activates procollagenase. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMP10
• Entrez:
  • 4319(Human)