MMP-10 Antibody (MM0024-9G10) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: MM0024-9G10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 594

MMP-10 Antibody (MM0024-9G10) [Alexa Fluor™ Plus 594] Summary

• Immunogen: Human recombinant MMP-10
• Specificity: This antibody recognizes human MMP-10 in western blot without cross reactivity other human MMPs.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Mouse
• Gene: MMP10
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

This antibody is reactive against human. Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MMP-10 Antibody (MM0024-9G10) [Alexa Fluor™ Plus 594]

• EC 3.4.24
• EC 3.4.24.22
• matrix metallopeptidase 10 (stromelysin 2)
• matrix metalloprotease 10
• matrix metalloproteinase 10 (stromelysin 2)
• Matrix metalloproteinase-10
• MMP10
• MMP-10
• SL-2
• STMY2stromelysin-2
• Stromelysin 2
• transin 2
• transin-2

Background

Matrix metalloproteinases belong to a family of proteases that are essential for the breakdown of extracellular matrix (ECM), thus they play an important role in apoptosis, and tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most of the MMP's contain a common domain structures, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 belongs to the Stromelysin group of proteases. Stromelysins degrade ECM proteoglycans, laminin, fibronectin and gelatin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMP10