MLC1 Antibody

Western Blot: MLC1 Antibody [NBP2-26196] - Staining of Hippocampus lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

• Reactivity: Hu
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

MLC1 Antibody Summary

• Description: Novus Biologicals Goat MLC1 Antibody (NBP2-26196) is a polyclonal antibody validated for use in IHC, WB and ELISA. Anti-MLC1 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-SDSANILDEVPFPAR corresponding to internal region according to NP_055981.1.
• Specificity: Reported variants represent identical protein: NP_631941.1, NP_055981.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: MLC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Peptide ELISA Detection limit 1:128000
  • Western Blot 1 - 3 ug/ml
• Application Notes: WB: Approx. 70 kDa band observed in human brain is reported in scientific literature (PMID: 21624973).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for MLC1 Antibody

• LVM
• megalencephalic leukoencephalopathy with subcortical cysts 1
• WKL1

Background

The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MLC1 Antibody (NBP2-26196)(1)

Publication using NBP2-26196

• Lopez-Hernandez T, Sirisi S, Capdevila-Nortes X et al. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet. 2011-06-07 [PMID: 21624973]

Bioinformatics

• Gene Symbol: MLC1
• Entrez:
  • 23209(Rat)
  • 23209(Rat)