MKS1 Antibody

Images

 
Western Blot: MKS1 Antibody [NBP1-88692] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells), Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
Western Blot: MKS1 Antibody [NBP1-88692] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-345
Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human colon shows strong cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human fallopian tube.
Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human kidney.
Immunohistochemistry-Paraffin: MKS1 Antibody [NBP1-88692] - Staining of human colon.
Independent Antibodies: Staining of human colon, fallopian tube, kidney and liver using NBP1-88692 (A) shows similar protein distribution across tissues to independent antibody NBP1-88691 (B).

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

MKS1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EVPSFLVERMANVRRRRQDRRGMEGGILKSRIVTWEPSEEFVRNNHVINTPLQTMHIMADLGPYKKLGYKKYEHVLCTLKVDSNGVITVKPDFTGLKGPYRI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MKS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04 - 0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MKS1 Protein (NBP1-88692PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MKS1 Antibody

  • BBS13FLJ20345
  • FABB proteome-like protein
  • Meckel syndrome type 1 protein
  • Meckel syndrome, type 1
  • MES
  • MKS
  • POC12 centriolar protein homolog
  • POC12

Background

MKPX, also known as JSP-1 for Jnk Stimulatory Phosphatase-1, belongs to the LMW-DSP subfamily of phosphatases. MKPX has been shown to have the capacity to activate the c-Jun N-terminal kinase (Jnk) signaling pathway. The activation of Jnk has been implicated in a number of important physiological processes, including embryonic morphogenesis, cell survival and apoptosis. At least two mRNA transcripts have been reported. Jnk signaling has been linked to human disease conditions, such as tumor development, cardiac hypertrophy, ischemia/reperfusion injury, diabetes, hyperglycemia-induced apoptosis, and several neurodegenerative disorders.MKPX has been shown to be widely expressed with highest expression in heart, kidney, liver, lung, pancreas and placenta. ESTs have been isolated from a diverse set of human tissues libraries, especially blood and breast.Caution: The acronym MKPX also has been used to describe Dual Specificity Protein Phosphatase 7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for MKS1 Antibody (NBP1-88692)

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Blogs on MKS1

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Bioinformatics

Gene Symbol MKS1