Meckelin Antibody

Images

 
Western Blot: Meckelin Antibody [NBP1-06590] - Immunodetection of Meckelin (120kDa) in whole cell extracts of HEK293 cells.
Immunohistochemistry-Paraffin: Meckelin Antibody [NBP1-06590] - Staining of kidney tissue section with Meckelin Antibody (NBP1-06590).

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-Fr, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Meckelin Antibody Summary

Immunogen
Synthetic peptide derived from Cter domain of human Meckelin protein
Specificity
Reacts specifically with human 111 kDa protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMEM67
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:1000
  • Immunocytochemistry/Immunofluorescence 1:10-1:500
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Frozen 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
IHC-Frozen, ICC/IF applications reported in scientific literature (PMID: 23516626)
Control Peptide
Publications
Read Publication using
NBP1-06590 in the following applications:

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 23516626). Predicted to cross react with many other species like guinea pig, sheep, cat, dog, pig due to sequence identity.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Antiserum
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Lyophilized powder, reconstituted in distilled water.

Alternate Names for Meckelin Antibody

  • meckel syndrome type 3 protein
  • Meckelin
  • MGC26979
  • TNEM67
  • transmembrane protein 67

Background

Meckelin localizes to the primary cilium and to the plasma membrane. It functions in centriole migration to the apical membrane and formation of the primary cilium. Defects in the gene are a cause of Meckel syndrome type 3 (MKS3) and Joubert syndrome type 6 (JBTS6).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Meckelin Antibody (NBP1-06590)(1)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 2 applications: ICC/IF, IHC-Fr.


Filter By Application
ICC/IF
(1)
IHC-Fr
(1)
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Filter By Species
Rat
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Meckelin Antibody (NBP1-06590) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for Meckelin Antibody (NBP1-06590)

Discover related pathways, diseases and genes to Meckelin Antibody (NBP1-06590). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Calculators

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Bioinformatics

Gene Symbol TMEM67
Entrez
Uniprot