MKK7/MEK7 Antibody (324302) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: IHC
• Clone: 324302
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

MKK7/MEK7 Antibody (324302) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human MKK7
  Met1-Arg419
  Accession # O14733
• Specificity: Detects rhMKK7 in direct ELISAs. This antibody does not cross-react with rhMKK4.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MKK7/MEK7 Antibody (324302) [Alexa Fluor® 488]

• c-Jun N-terminal kinase kinase 2
• dual specificity mitogen-activated protein kinase kinase 7
• EC 2.7.12.2
• JNK kinase 2
• JNK-activating kinase 2
• JNKK 2
• JNKK2
• MAP kinase kinase 7
• MAP2K7
• MAPK/ERK kinase 7
• MAPKK7
• MEK 7
• MEK7
• mitogen-activated protein kinase kinase 7
• MKE7
• MKK7
• MKK7MAPKK 7
• PRKMK7

Background

Mitogen-activated protein kinase kinase 7 (MKK7 or MAP2K7), also known as Jun kinase kinase 2 (JNKK2), is activated by proinflammatory cytokines and environmental stresses. Activation occurs through phosphorylation at Ser 271 and Thr 275 by several upstream MAPK kinase kinases (MAP3Ks). MKK7 is a dual specificity protein kinase, phosphorylating and activating the JNK family of MAP kinases at Thr and Tyr positions within the phosphoacceptor sequence Thr-Pro-Tyr.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.