MKK7/MEK7 Products

Antibodies
MKK7/MEK7 Antibody (4E5)
MKK7/MEK7 Antibody (4E5)
NBP2-37542
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC
Host: Mouse Monoclonal
MKK7/MEK7 Antibody
MKK7/MEK7 Antibody
AF3579
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
MKK7/MEK7 Antibody (2G5)
MKK7/MEK7 Antibody (2G5)
H00005609-M04
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, PLA
Host: Mouse Monoclonal
Lysates
MKK7/MEK7 Overexpression Lysa ...
MKK7/MEK7 Overexpression Lysate (D...
H00005609-T01
Species: Hu
Applications: WB
MKK7/MEK7 Overexpression Lysa ...
MKK7/MEK7 Overexpression Lysate (N...
NBP2-05503
Applications: WB
Proteins
MKK7/MEK7 Recombinant Protein ...
MKK7/MEK7 Recombinant Protein
H00005609-P01
Species: Hu
Applications: WB, ELISA, PA
MKK7/MEK7 Partial Recombinant ...
MKK7/MEK7 Partial Recombinant Protein
H00005609-Q01
Species: Hu
Applications: WB, ELISA, PA
MKK7/MEK7 Recombinant Protein ...
MKK7/MEK7 Recombinant Protein Antigen
NBP1-87792PEP
Species: Hu
Applications: AC
RNAi
MKK7/MEK7 RNAi
MKK7/MEK7 RNAi
H00005609-R02
Species: Hu

Description

c-Jun NH2-terminal protein kinase (JNK), a distant member of the mitogen-activated protein (MAP) kinase family, regulates gene expression in response to various extracellular stimuli. MKK7, a novel member of the MAP kinase kinase family, was phosphorylated and activated by MEKK1, a MAP kinase kinase kinase in the JNK signaling cascade. MKK7 activity was also stimulated by constitutively active forms of Rac and Cdc42Hs, members of the Rho small GTP-binding protein family (1). endogenous MKK7 was activated by treatment with the growth factor interleukin-3 (but not interleukin-4), or by ligation of CD40, the B-cell antigen receptor, or the receptor for the Fc fragment of immunoglobulin. MKK7 was also activated when cells were exposed to heat, UV irradiation, anisomycin, hyperosmolarity or the pro-inflammatory cytokine tumor necrosis factor-alpha, suggesting that MKK7 is involved in many physiological pathways (2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 5609
Alternate Names
  • MAP kinase kinase 7
  • MEK7
  • JNKK 2
  • JNKK2
  • JNK-activating kinase 2
  • dual specificity mitogen-activated protein kinase kinase 7
  • JNK kinase 2
  • MAPKK7
  • c-Jun N-terminal kinase kinase 2
  • EC 2.7.12.2
  • PRKMK7
  • MEK 7
  • Jnkk2
  • MKK7MAPKK 7
  • MAPK/ERK kinase 7
  • mitogen-activated protein kinase kinase 7

Research Areas for MKK7/MEK7

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

PTMs for MKK7/MEK7

Learn more about PTMs related to MKK7/MEK7.

Phosphorylation
Cleavage
Dephosphorylation
Ribosylation
Ubiquitination

Bioinformatics Tool for MKK7/MEK7

Discover related pathways, diseases and genes to MKK7/MEK7. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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