MKK7/MEK7 Antibody (2G5)

Images

 
Western Blot: MKK7/MEK7 Antibody (2G5) [H00005609-M04] - Analysis of MAP2K7 expression in transfected 293T cell line by MAP2K7 monoclonal antibody (M04), clone 2G5. Lane 1: MAP2K7 transfected lysatE (47.485 KDa). Lane ...read more
Immunocytochemistry/ Immunofluorescence: MKK7/MEK7 Antibody (2G5) [H00005609-M04] - Analysis of monoclonal antibody to MAP2K7 on HeLa cell. Antibody concentration 10 ug/ml
Immunohistochemistry-Paraffin: MKK7/MEK7 Antibody (2G5) [H00005609-M04] - Analysis of monoclonal antibody to MAP2K7 on formalin-fixed paraffin-embedded human pancreas. Antibody concentration 1.2 ug/ml
Proximity Ligation Assay: MKK7/MEK7 Antibody (2G5) [H00005609-M04] - Analysis of protein-protein interactions between MAPK8 and MAP2K7. HeLa cells were stained with anti-MAPK8 rabbit purified polyclonal 1:1200 and ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC-P, PLA
Clone
2G5
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

MKK7/MEK7 Antibody (2G5) Summary

Immunogen
MAP2K7 (NP_660186, 1 a.a. - 99 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPRPTLQLPLANDGGSRSPSSESSPQHPTPPARPRHMLGLPSTLFTPRSMESIEIDQKLQEI
Localization
Cytoplasmic and Nuclear
Specificity
MAP2K7 - mitogen-activated protein kinase kinase 7
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MAP2K7
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Paraffin
  • Proximity Ligation Assay
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for IHC-P and ELISA.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MKK7/MEK7 Antibody (2G5)

  • c-Jun N-terminal kinase kinase 2
  • dual specificity mitogen-activated protein kinase kinase 7
  • EC 2.7.12.2
  • JNK kinase 2
  • JNK-activating kinase 2
  • JNKK 2
  • JNKK2
  • MAP kinase kinase 7
  • MAP2K7
  • MAPK/ERK kinase 7
  • MAPKK7
  • MEK 7
  • MEK7
  • mitogen-activated protein kinase kinase 7
  • MKE7
  • MKK7
  • MKK7MAPKK 7
  • PRKMK7

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MAP2K7
Entrez
OMIM
Uniprot