MIXL1 Antibody (868132) [mFluor Violet 610 SE]

• Reactivity: Mu
• Applications: ICC/IF
• Clone: 868132
• Clonality: Monoclonal
• Host: Rat
• Conjugate: mFluor Violet 610 SE

MIXL1 Antibody (868132) [mFluor Violet 610 SE] Summary

• Immunogen: E. coli-derived recombinant mouse MIXL1
  Lys147-Phe231
  Accession # Q9WVI0
• Specificity: Detects mouse MIXL1 in ELISAs.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: MIXL1
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MIXL1 Antibody (868132) [mFluor Violet 610 SE]

• hMix
• homeobox protein MIXL1
• Homeodomain protein MIX
• MGC138179
• MILD1
• Mix.1 homeobox-like protein
• Mix1 homeobox (Xenopus laevis)-like 1
• Mix1 homeobox-like 1 (Xenopus laevis)
• MIX1 homeobox-like protein 1
• MIXL1
• Mix-like homeobox protein 1
• MIXLMIX

Background

MIXL1, also known as Homeobox protein MIXL1, is a 232 amino acid protein that is 25 kDa, restricted to progenitors and secondary lymph tissues, acts as an important transcription factor in proper axial mesendoderm morphogenesis and endoderm formation, needed for efficient differentiation of cells from the primitive streak stage to blood by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages, participates in the morphogenesis of the heart and the gut during embryogenesis, and acts as a negative regulator of brachyury expression. Studies of this protein are being performed on research about uterine inversion, vascular dementia, Hodgkin's lymphoma, dementia, cholera, and hematopoiesis. OMA1 protein has been shown to interact with ALX4, DLX1, GTF2E1, IRF9, NEUROD1, NKX2-1, POU4F2, and TLE6 proteins in adipogenesis pathway and endoderm formation, hematopoietic progenitor cell differentiation, transcription, DNA-dependent, gastrulation, endoderm development, heart development, and digestive tract development processes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MIXL1