MIXL1 Products

Description

MIXL1, also known as Homeobox protein MIXL1, is a 232 amino acid protein that is 25 kDa, restricted to progenitors and secondary lymph tissues, acts as an important transcription factor in proper axial mesendoderm morphogenesis and endoderm formation, needed for efficient differentiation of cells from the primitive streak stage to blood by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages, participates in the morphogenesis of the heart and the gut during embryogenesis, and acts as a negative regulator of brachyury expression. Studies of this protein are being performed on research about uterine inversion, vascular dementia, Hodgkin's lymphoma, dementia, cholera, and hematopoiesis. OMA1 protein has been shown to interact with ALX4, DLX1, GTF2E1, IRF9, NEUROD1, NKX2-1, POU4F2, and TLE6 proteins in adipogenesis pathway and endoderm formation, hematopoietic progenitor cell differentiation, transcription, DNA-dependent, gastrulation, endoderm development, heart development, and digestive tract development processes.

Bioinformatics

Entrez	83881 Human
Uniprot	NP_114150 Human
Product By Gene ID	83881
Alternate Names	hMix homeobox protein MIXL1 Homeodomain protein MIX MGC138179 MILD1 Mix.1 homeobox-like protein Mix1 homeobox (Xenopus laevis)-like 1 Mix1 homeobox-like 1 (Xenopus laevis) MIX1 homeobox-like protein 1 Mix-like homeobox protein 1 MIXLMIX