MiRP2 Antibody

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Immunohistochemistry-Paraffin: MiRP2 Antibody [NBP1-49885] - 3.75ug/ml staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, CaSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

MiRP2 Antibody Summary

Immunogen
Peptide with sequence C-PDNQTEERRASLP corresponding to internal region according to NP_005463.1.
Epitope
PDNQTEERRASLP - Internal region
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
KCNE3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1ug/ml
  • Immunohistochemistry-Paraffin
  • Peptide ELISA Detection limit 1:1000
  • Western Blot detection limit 1:1000
Application Notes
Western blot: Preliminary experiments in Human, Mouse and Rat Skeletal Muscle lysates gave no specific signal but low background
IHC: Paraffin embedded Human Kidney.
Publications
Read Publication using NBP1-49885.

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, Bovine, Porcine

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MiRP2 Antibody

  • cardiac voltage-gated potassium channel accessory subunit
  • DKFZp781H21101
  • HOKPPMGC102685
  • HYPP
  • MGC129924
  • Minimum potassium ion channel-related peptide 2
  • MinK-related peptide 2
  • MiRP2
  • Potassium channel subunit beta MiRP2
  • potassium voltage-gated channel subfamily E member 3
  • potassium voltage-gated channel, Isk-related family, member 3
  • voltage-gated K+ channel subunit MIRP2

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MiRP2 Antibody (NBP1-49885)(1)

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Video Protocols

WB Video Protocol

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Bioinformatics

Gene Symbol KCNE3
Entrez
Uniprot