Potassium Channel Kv3.1 [p Ser503] Antibody

Images

 
Immunohistochemistry: Kv3.1 [p Ser503] Antibody [NB300-279] - IHC staining of medial nucleus of the trapezoid body (MNTB) cells with the phospho-Ser503 Kv3.1 subunit antibody. The left panel shows control cells. The ...read more

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, IHC, IHC-Fr
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Potassium Channel Kv3.1 [p Ser503] Antibody Summary

Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser503 conjugated to KLH. Accession # P25122
Modification
p Ser503
Specificity
Specific for the ~100k Kv3.1 voltage-gated potassium channel protein phosphorylated at Ser503.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNC1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Frozen 1:1000
  • Western Blot 1:1000
Theoretical MW
100 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using NB300-279.

Reactivity Notes

Tested in Rat and Mouse.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10mM HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Potassium Channel Kv3.1 [p Ser503] Antibody

  • FLJ41162
  • FLJ42249
  • FLJ43491
  • KCNC1
  • Kv3.1
  • KV4
  • MGC129855
  • NGK2
  • Potassium Channel Kv3.1
  • potassium voltage-gated channel subfamily C member 1
  • potassium voltage-gated channel, Shaw-related subfamily, member 1
  • voltage-gated potassium channel protein KV3.1
  • Voltage-gated potassium channel subunit Kv3.1
  • Voltage-gated potassium channel subunit Kv4

Background

Voltage-gated K+ channels are important determinants of neuronal membrane excitability. Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types (Maletic-Savatic et al., 1995; Pongs, 1999; Blaine and Ribera, 1998; Burger and Ribera, 1996). The Kv3.1 potassium channel is expressed at high levels in neurons that characteristically fire rapid trains of action potentials (Gan et al., 1999). Particularly high levels of this channel are found in neurons of the auditory brainstem. These neurons appear to participate in neural circuits that determine the intensity and timing of auditory stimuli and use this information to determine the location of sounds in space (von Hehn et al., 2004).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Potassium Channel Kv3.1 Antibody (NB300-279)(6)

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Bioinformatics

Gene Symbol KCNC1
Entrez
Uniprot