MiRP2 Products

Description

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. (provided by RefSeq)

Bioinformatics

Entrez	10008 Human
Uniprot	NM_005472 Human NP_005463.1 Human Q9Y6H6 Human
Product By Gene ID	10008
Alternate Names	cardiac voltage-gated potassium channel accessory subunit DKFZp781H21101 HOKPPMGC102685 HYPP MGC129924 Minimum potassium ion channel-related peptide 2 MinK-related peptide 2 MiRP2 Potassium channel subunit beta MiRP2 potassium voltage-gated channel subfamily E member 3 potassium voltage-gated channel, Isk-related family, member 3 voltage-gated K+ channel subunit MIRP2

Diseases related to MiRP2

Discover more about diseases related to MiRP2.

Periodic Paralysis (finding)
Hypokalemic Periodic Paralysis
Cardiac Arrhythmia
Long Qt Syndrome
Cardiac Fibrillation
Atrial Fibrillation
Thyrotoxicosis
Weakness
Cystic Fibrosis
Familial Periodic Paralysis
Thyrotoxic Periodic Paralysis
Fibrosis
Brugada Syndrome (disorder)
Heart Diseases
Muscle Weakness
Channelopathies
Hyperkalemic Periodic Paralysis
Meniere Disease
Chimera Disorder
Graves Disease

Pathways for MiRP2

View related products by pathway and learn more about each of the pathways below.

Secretion
Transport
Localization
Pathogenesis
Acid Secretion
Ion Transport
Gastric Acid Secretion
Cell Cycle
Gene Silencing
Chloride Transport
G1 Phase
Cell Cycle Arrest
Membrane Depolarization
Cell Death
Prolactin Secretion
Heart Development
Rna Interference
Regulation Of Blood Pressure

PTMs for MiRP2

Learn more about PTMs related to MiRP2.

Phosphorylation
Biotinylation
Hydroxylation
Dephosphorylation

Bioinformatics Tool for MiRP2

Discover related pathways, diseases and genes to MiRP2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.