MICL/CLEC12A Antibody

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Western Blot: MICL/CLEC12A Antibody [NBP2-27346] - Analysis of CLEC12A using CLEC12A antibody. ThP1 cell lysate in the 1) absence and 2) presence of immunizing peptide probed with 2 ug/ml of CLEC12A antibody. I goat ...read more

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

MICL/CLEC12A Antibody Summary

Immunogen
A portion of amino acids170-220 from human CLEC12A was used as the immunogen.
Predicted Species
Chimpanzee (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CLEC12A
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 2-4ug/ml
Publications
Read Publication using
NBP2-27346 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 0.05% BSA
Preservative
0.05% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A purified

Alternate Names for MICL/CLEC12A Antibody

  • CD371
  • CLEC12A
  • CLL1
  • CLL-1
  • C-type lectin domain family 12, member A
  • DCAL-2
  • MICL

Background

CLEC12A is also known as MICL or Myeloid inhibitory C-type lectin receptor, and is a member of the C-type lectin receptor superfamily (1). C-type lectins are important innate immune receptors detecting PAMPs and enhancing antigen specific responses among a very diverse role. Often lectins may enhance cell-cell interactions and also mediate pathogen recognition using C-type lectin receptors (2). CLEC12A expression has been found in normal myeloid cells and in acute myeloid leukemia cells, neutrophils, eosinophils, monocytes and dendritic cells. CLEC12A has also been found to act as an enhancer of immune responses - CLEC12A monoclonal antibody enhances specific antibody responses (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MICL/CLEC12A Antibody (NBP2-27346)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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Bioinformatics

Gene Symbol CLEC12A
Uniprot