MHC Class I Antibody (MEM-E/06) [PE]

Images

 
Flow Cytometry: MHC Class I Antibody (MEM-E/06) [PE] [NB500-307PE] - A cell surface stain was performed on THP-1 cells with MHC Class I antibody (MEM-E/06) NB500-307 (blue) and a matched isotype control NBP2-27287 ...read more

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications Flow, IHC, IHC-P, IP
Clone
MEM-E/06
Clonality
Monoclonal
Host
Mouse

MHC Class I Antibody (MEM-E/06) [PE] Summary

Immunogen
Bacterially expressed recombinant full length protein refolded with beta2-microglobulin and peptide (Human).
Localization
Type I membrane protein.
Specificity
This antibody (clone MEM-E/06) recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. Some resultss showed that this antibody cross-reacts with some classical MHC Class I molecules (HLA-A3, -A11, -B7). However, others have confirmed that this antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32, -B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HLA-E
Purity
Protein A purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Conjugate
PE
Format
PE (A=488, E=575)
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation

Alternate Names for MHC Class I Antibody (MEM-E/06) [PE]

  • DKFZp686P19218
  • EA1.2
  • EA2.1
  • HLA class I histocompatibility antigen, alpha chain E
  • HLA class I histocompatibility antigen, E alpha chain
  • HLA-6.2
  • HLAE
  • lymphocyte antigen
  • major histocompatibility complex, class I, E
  • MHC class I antigen E
  • MHC HLA-E alpha-1
  • MHC HLA-E alpha-2.1
  • MHC
  • QA1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for MHC Class I Antibody (NB500-307PE) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Allophycocyanin Labeled NB500-307APC
DyLight 350 Labeled NB500-307UV
DyLight 405 Labeled NB500-307V
DyLight 405LS Labeled NB500-307V3
DyLight 488 Labeled NB500-307G
DyLight 680 Labeled NB500-307FR
DyLight 755 Labeled NB500-307IR
PerCP Labeled NB500-307PCP

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Blogs on MHC Class I.

MHC Class I and the Herpes Simplex Virus
MHC molecules (also known as major histocompatibility complex molecules) assist in the presentation of antigens to T cells in order to eradicate foreign pathogens.  These molecules are highly polymorphic, meaning that they exist in multiple varian...  Read full blog post.

Major Histocompatibility Complex (MHC) Class I
The products of MHC genes are antigen-presenting molecules (APMs) designed for antigen fragment (peptide) presentation to the T-cell receptor. In particular, MHC Class I molecules play a key role in the immune system by presenting endogenously synthes...  Read full blog post.

Contact Information

Product PDFs

Bioinformatics

Gene Symbol HLA-E

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