mGluR1 Antibody (1059503) [Alexa Fluor® 405]

• Reactivity: Hu
• Applications: IHC
• Clone: 1059503
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 405

mGluR1 Antibody (1059503) [Alexa Fluor® 405] Summary

• Immunogen: Synthetic peptide
  Accession # P42261
• Specificity: Detects mouse GluR1 in direct ELISA.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for mGluR1 Antibody (1059503) [Alexa Fluor® 405]

• glutamate receptor, metabotropic 1
• GPRC1A
• GRM1
• GRM1A
• metabotropic glutamate receptor 1
• mGluR1
• MGLUR1A
• MGLUR1GPRC1AmGlu1

Background

GluR1 is a 4-transmembrane protein that belongs to the glutamate-gated ion channel family. It is one of four AMPA receptor subunits that form a functional heterotetrameric glutamate receptor. GluR1 only interacts with GluR2. In addition to constitutive phosphorylation on a key serine in the C-terminal extracellular region, neurotransmitter-induced phosphorylation of another key serine by CaMKII leads to a potentiation of glutamate-mediated current.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.