Menin Antibody

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Western Blot: Menin Antibody [NB100-287] - Using the Biotin direct conjugate Samples: Whole cell lysate from HEK 293T (50, 15, and 5 ug). Antibody: Affinity purified, biotin-conjugated, goat anti-Menin antibody used at ...read more
Western Blot: Menin Antibody [NB100-287] - Samples: Whole cell lysate (40 ug for WB; one 10 cm plate 293T cells for IP) from 293T cells. Affinity purified goat anti-Menin used as indicated for IP. Menin was detected ...read more
Western Blot: Menin Antibody [NB100-287] - Analysis using the Biotin conjugate of NB100-287. Detection of HEK 293T (50, 15, and 5 ug). Antibody used at 1.0 ug/ml. Detection: Streptavidin-HRP and chemiluminescence with ...read more
Western Blot: Menin Antibody [NB100-287] - Samples: Whole cell lysate (50 ug) from HeLa and 293T cells prepared using NETN lysis buffer. Antibody: Affinity purified goat anti-Menin antibody used for WB at 0.1 ug/ml. ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human ASH2 (NB600-250). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human DBF4 (NB100-88114). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human FANCD2 (NBP1-22971). Image merged from DAPI (2ms) and ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human HCF1 (NB100-68209). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human HDAC1 (NB100-2241). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human HMG20B (NB100-57535). Image merged from DAPI (2ms) and ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human lQGAP1 (NBP1-06529). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human MLL1 (NB600-256). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugatge Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human NFKappaB1 (NB100-97827). Image merged from DAPI (2ms) and ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human NFKappaB2 (NB100-97829). Image merged from DAPI (2ms) and ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1(NB100-287). and rabbit anti-human p53 (NB200-171). Image merged from DAPI (2ms) and Texas Red ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human phospho-RELA [S468] (NBP1-19105). Image merged from DAPI ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human phospho-POLR2A[S2] (NB100-1805). Image merged from DAPI ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human RPA2 (NB100-332). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human phospho-RPA2 [S33] (NB100-544). Image merged from DAPI ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human phospho-RPA2 [S4/S8] (NBP1-23017). Image merged from DAPI ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human SIN3A (NB100-2254). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human STUB1 (NB100-77315). Image merged from DAPI (2ms) and ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1(NB100-287) and rabbit anti-human TRX2 (NB600-254). Image merged from DAPI (2ms) and Texas Red ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human VIM (NB100-81644). Image merged from DAPI (2ms) and Texas ...read more
Proximity Ligation Assay: Menin Antibody [NB100-287] - Secondary-conjugate Duolink II PLA in Hela cells. goat anti-human MEN1 (NB100-287) and rabbit anti-human WDR5 (NBP1-30070). Image merged from DAPI (2ms) and Texas ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, IP, PLA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
1.0 mg/ml
   

Biological Strategies

     

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price

Menin Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 575 and the C-terminus (residue 615) of human Multiple Endocrine Neoplasia 1 using the numbering given in entry NP_000235.2 (GeneID 4221).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
MEN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:10000
  • Immunoprecipitation 2-10 ug/mg lysate
  • Proximity Ligation Assay 1:1000-1:10000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Menin Antibody

  • MEAI
  • MEN1
  • Menin
  • multiple endocrine neoplasia I
  • multiple

Background

Menin is the gene product of the putative tumor suppressor MEN1 associated with the syndrome termed multiple endocrine neoplasia type 1 that may function in the regulation of DNA synthesis or the response to DNA damage. Menin has been shown to interact with JunD, a member of the AP-1 heterodimer and inhibit transcription. Menin has also been shown to interact with Pem, FANCD2, RPA, NMMHCII-A, GFAP, vimentin, Hsp70, NfkappaB proteins, Smads, mSin3A and is part of the MLL2 and MLL1 Set1-like histone H3 K4 methyltransferase complex where it interacts directly with ASH2, Rbbp5, and WDR5. As part of the MLL complexes, menin may mediate its tumor suppressor activity via the regulation of histone methylation of HOX and CDK inhibitor genes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol MEN1
Entrez
Uniprot