Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC-Fr, IHC-P
Clone
M2-7C10 + M2-9E3 + T311 + HMB45
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 550

Order Details

Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (M2-7C10 + M2-9E3 + T311 + HMB45) [DyLight 550] Summary

Immunogen
Recombinant hMART-1 protein (M2-7C10; M2-9E3); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Localization
Cytoplasmic
Specificity
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Isotype
IgG2b/IgG2a/IgG1
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Array

  • MART1
  • MART-1
  • melan-A
  • MLANA

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34681AF350
Alexa Fluor 405 NBP2-34681AF405
Alexa Fluor 488 NBP2-34681AF488
Alexa Fluor 532 NBP2-34681AF532
Alexa Fluor 594 NBP2-34681AF594
Alexa Fluor 647 NBP2-34681AF647
Alexa Fluor 700 NBP2-34681AF700
Alexa Fluor 750 NBP2-34681AF750
Biotin NBP2-34681B
DyLight 350 NBP2-34681UV
DyLight 405 NBP2-34681V
DyLight 488 NBP2-34681G
DyLight 550 NBP2-34681R
DyLight 594 NBP2-34681DL594
DyLight 650 NBP2-34681C
DyLight 680 NBP2-34681FR
DyLight 755 NBP2-34681IR
HRP NBP2-34681H
Janelia Fluor 549 NBP2-34681JF549
Janelia Fluor 646 NBP2-34681JF646

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