A synthetic peptide that maps to a region between residues 1 and 50 of human Cofactor Required for Sp1 transcriptional activation, subunit 3 using the numbering given in Swiss-Prot entry Q9ULK4 (GeneID 9439).
NB200-337 is specific for human CRSP 3 protein.
Rat (100%). Backed by our 100% Guarantee.
Immunogen affinity purified
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Optimal working dilutions should be determined experimentally by the investigator. Prepare working dilution immediately before use. Western Blot: Not Recommended, use NB 200-339 for WB. *In some cases, the antibody may be diluted further than indicated. Use in chromatin immunoprecipitation reported in scientific literature (PMID 25892301)
Mouse reactivity reported in scientific literature (PMID: 25892301).
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for MED23 Antibody
130 kDa transcriptional co-activator
133 kDa transcriptional co-activator
mediator complex subunit 23CRSP133
Protein sur-2 homolog
subunit 3, 130kDa
Transcriptional coactivator CRSP130
Vitamin D3 receptor-interacting protein complex 130 kDa component
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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