MAP4K5 Antibody [DyLight 755]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 755

MAP4K5 Antibody [DyLight 755] Summary

• Immunogen: E. coli-derived recombinant human MAP4K5
  Lys395-Asn484 (Asn473Lys)
  Accession # Q9Y4K4
• Specificity: Detects human MAP4K5 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: MAP4K5
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for MAP4K5 Antibody [DyLight 755]

• EC 2.7.11
• EC 2.7.11.1
• GCKR
• germinal center kinase-related
• KHS1
• KHSMEKKK 5
• Kinase homologous to SPS1/STE20
• MAP4K5
• MAPK/ERK kinase kinase kinase 5
• MAPKKKK5
• MEK kinase kinase 5
• mitogen-activated protein kinase kinase kinase kinase 5

Background

MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAP4K5