MAP4K5 Products

Description

MAP4K5 encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Bioinformatics

Entrez	11183 Human
Uniprot	AAH36013 Human NM_198794 Human NP_006566 Human NP_006566.2 Human Q9Y4K4 Human
Product By Gene ID	11183
Alternate Names	EC 2.7.11 EC 2.7.11.1 GCKR germinal center kinase-related KHS1 KHSMEKKK 5 Kinase homologous to SPS1/STE20 MAPK/ERK kinase kinase kinase 5 MAPKKKK5 MEK kinase kinase 5 mitogen-activated protein kinase kinase kinase kinase 5

Research Areas for MAP4K5

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Protein Kinase