LZTS1 Antibody - BSA Free

Western Blot: LZTS1 Antibody [NBP2-17195] - Sample (30 ug of whole cell lysate) A: U87-MG 7. 5% SDS PAGE gel, diluted at 1:1000.

Immunohistochemistry-Paraffin: LZTS1 Antibody [NBP2-17195] - Human breast cancer, using FEZ1 antibody at 1:250 dilution. Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min.

• Reactivity: Hu, Rt, Bv
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

LZTS1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit LZTS1 Antibody - BSA Free (NBP2-17195) is a polyclonal antibody validated for use in IHC and WB. Anti-LZTS1 Antibody: Cited in 2 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human LZTS1. The exact sequence is proprietary.
• Localization: Cytoplasm (By similarity); Cell membrane (By similarity); Cell projection; dendritic spine (By similarity); Cell junction; synapse; postsynaptic cell membrane; postsynaptic density (By similarity); synapse (By similarity)
• Predicted Species: Rat (92%), Bovine (90%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LZTS1
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 67 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%).

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for LZTS1 Antibody - BSA Free

• F37
• F37/esophageal cancer-related gene-coding leucine-zipper motifFez1
• FEZ1leucine zipper putative tumor suppressor 1
• leucine zipper, putative tumor suppressor 1

Background

This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for LZTS1 Antibody (NBP2-17195)(2)

Publications using NBP2-17195

• Lopez-Ozuna Vm, Kogan L, Hachim My Et Al. Identification of Predictive Biomarkers for Lymph Node Involvement in Obese Women With Endometrial Cancer Frontiers in oncology 2021-07-07 [PMID: 34307159] (Western Blot, Human)
• Hou X, Niu Z, Liu L et al. miR-1207-5p regulates the sensitivity of triple-negative breast cancer cells to Taxol treatment via the suppression of LZTS1 expression Oncol Lett 2019-01-01 [PMID: 30655858] (WB, Human)

Bioinformatics

• Gene Symbol: LZTS1
• Uniprot:
  • Q9Y250(Human)