Lysine Hydroxylase 2/PLOD2 Antibody (408105) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 408105
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

Lysine Hydroxylase 2/PLOD2 Antibody (408105) [Alexa Fluor® 488] Summary

• Immunogen: S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Lysine Hydroxylase 2/PLOD2
  Ala26-Pro758
  Accession # NP_891988
• Specificity: Detects human Lysine Hydroxylase 2/PLOD2 in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Lysine Hydroxylase 2/PLOD2 Antibody (408105) [Alexa Fluor® 488]

• 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2
• 2-oxoglutarate 5-dioxygenase 2
• LH2
• Lysine Hydroxylase 2
• PLOD2
• procollagen-lysine
• telopeptide lysyl hydroxylase
• TLH

Background

Lysine Hydroxylase 2 (LH2) also known as PLOD2 (procollagen-lysine, 2 oxoglutarate 5 dioxygenase 2) is a membrane-bound homodimeric enzyme localized to the cisternae of the rough ER. The enzyme catalyzes the hydroxylation of lysine residues in collagen-like peptides, which in turn serves as sites for carbohydrate attachment in collagen. Two alternatively spliced forms have 737 or 758 amino acids (aa). Human LH2 (758 aa form) shares 92.5% aa sequence identity with the appropriate isoform of mouse and rat LH2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.