Lysine Hydroxylase 2/PLOD2 Products

Antibodies
Lysine Hydroxylase 2/PLOD2 An ...
Lysine Hydroxylase 2/PLOD2 Antibody
H00005352-B01P
Species: Hu, Rt
Applications: WB, ELISA, ICC/IF
Host: Mouse Polyclonal
Lysine Hydroxylase 2/PLOD2 An ...
Lysine Hydroxylase 2/PLOD2 Antibod...
NBP2-46451
Species: Hu
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
Lysine Hydroxylase 2/PLOD2 An ...
Lysine Hydroxylase 2/PLOD2 Antibod...
MAB4445
Species: Hu
Applications: WB, IP
Host: Mouse Monoclonal
Antibody Pairs
Lysine Hydroxylase 2/PLOD2 An ...
Lysine Hydroxylase 2/PLOD2 Antibod...
H00005352-PW1
Species: Hu
Applications: WB, IP
Lysates
Lysine Hydroxylase 2/PLOD2 Ov ...
Lysine Hydroxylase 2/PLOD2 Overexp...
H00005352-T01
Species: Hu
Applications: WB
Lysine Hydroxylase 2/PLOD2 Ov ...
Lysine Hydroxylase 2/PLOD2 Overexp...
NBL1-14522
Applications: WB
Proteins
Lysine Hydroxylase 2/PLOD2 Re ...
Lysine Hydroxylase 2/PLOD2 Recombi...
H00005352-P01
Species: Hu
Applications: WB, ELISA, PA
Lysine Hydroxylase 2/PLOD2 Re ...
Lysine Hydroxylase 2/PLOD2 Recombi...
H00005352-P02
Species: Hu
Applications: WB, ELISA, PA
RNAi
Lysine Hydroxylase 2/PLOD2 RN ...
Lysine Hydroxylase 2/PLOD2 RNAi
H00005352-R02
Species: Hu
Lysine Hydroxylase 2/PLOD2 RN ...
Lysine Hydroxylase 2/PLOD2 RNAi
H00005352-R01
Species: Hu

Description

PLOD2 is encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 5352
Alternate Names
  • telopeptide lysyl hydroxylase
  • 2-oxoglutarate 5-dioxygenase (lysine hydroxylase) 2
  • 2-oxoglutarate 5-dioxygenase 2
  • procollagen-lysine

PTMs for Lysine Hydroxylase 2/PLOD2

Learn more about PTMs related to Lysine Hydroxylase 2/PLOD2.

Hydroxylation

Bioinformatics Tool for Lysine Hydroxylase 2/PLOD2

Discover related pathways, diseases and genes to Lysine Hydroxylase 2/PLOD2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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