Lymphotoxin-alpha/TNF-beta Antibody

Western Blot: Lymphotoxin-alpha/TNF-beta Antibody [H00004049-D01P] - Analysis of LTA expression in transfected 293T cell line by LTA polyclonal antibody.Lane 1: LTA transfected lysate(22.30 KDa).Lane 2: Non-transfected lysate.

Product Discontinued

Lymphotoxin-alpha/TNF-beta Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: LTA (AAH34729.1, 1 a.a. - 205 a.a.) full-length human protein. MTPPERLFLPRVRGTTLHLLLLGLLLVLLPGAQGLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLWRANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQKMVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAFAL
• Specificity: LTA - lymphotoxin alpha (TNF superfamily, member 1),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LTA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Lymphotoxin-alpha/TNF-beta Antibody

• LT
• LTA
• LT-alpha
• lymphotoxin alpha (TNF superfamily, member 1)
• Lymphotoxin alpha
• Lymphotoxinalpha
• Lymphotoxin-alpha
• tnfb
• TNF-beta
• TNFBlymphotoxin-alpha
• TNFSF1
• TNFSF1B
• TNFSF1TNF-beta
• tumor necrosis factor beta
• Tumor necrosis factor ligand superfamily member 1

Background

Lymphotoxin alpha, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers with lymphotoxin-beta which anchors lymphotoxin-alpha to the cell surface. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. LTA is also involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Lymphotoxin-alpha/TNF-beta Antibody (H00004049-D01P)(2)

Publications using H00004049-D01P

• Pandey GN, Rizavi HS, Zhang H, Ren X et al. Abnormal gene and protein expression of inflammatory cytokines in the postmortem brain of schizophrenia patients. Schizophr Res 2017-05-02 [PMID: 28476335]
• Jeong JY, Kim KS, Moon JS et al. Targeted inhibition of phosphatidyl inositol-3-kinase p110b, but not p110alpha, enhances apoptosis and sensitivity to paclitaxel in chemoresistant ovarian cancers. Apoptosis. 2013-01-31 [PMID: 23371322]

Bioinformatics

• Gene Symbol: LTA
• Entrez:
  • 4049(Human)
• Uniprot:
  • AAH34729.1(Human)