Lymphotoxin-alpha/TNF-beta Antibody (15A3)

Product Discontinued

Lymphotoxin-alpha/TNF-beta Antibody (15A3) Summary

• Immunogen: Recombinant human LTA (35-205aa) purified from E. coli.
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: LTA
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:250
  • Western Blot 1:250-1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 10% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for Lymphotoxin-alpha/TNF-beta Antibody (15A3)

• LT
• LTA
• LT-alpha
• lymphotoxin alpha (TNF superfamily, member 1)
• Lymphotoxin alpha
• Lymphotoxinalpha
• Lymphotoxin-alpha
• tnfb
• TNF-beta
• TNFBlymphotoxin-alpha
• TNFSF1
• TNFSF1B
• TNFSF1TNF-beta
• tumor necrosis factor beta
• Tumor necrosis factor ligand superfamily member 1

Background

Lymphotoxin-alpha (LT-alpha; LTA) is member of the TNF ligand superfamily, bind the same TNF receptor and mediate similar pleiotropic effect. LTA, located within the MHC III region of chromosome 6, show close linkage to the HLA class I (HLA-B) and class II (HLA-DR) genes. LTA is proinflammatory cytokine with important biological activity and immunomodulatory function and be known to influence a variety of cellular response. In particular, Polymorphism in the gene encoding LTA appears to contribute to infectious disease susceptibility and infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LTA
• Entrez:
  • 4049(Human)
• Uniprot:
  • NP_001153212(Human)