LXR alpha/NR1H3 Antibody

Product Discontinued

LXR alpha/NR1H3 Antibody Summary

• Immunogen: Synthetic peptide corresponding to residues T(35) C I L R E E A R M P Q S T G(49) of mouse LXR alpha.
• Localization: Nuclear
• Specificity: Detects LXR alpha in mouse samples.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NR1H3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS with 1 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for LXR alpha/NR1H3 Antibody

• alpha
• Liver X receptor alpha
• liver X receptor-alpha
• LXR alpha
• LXRA
• NR1H3
• Nuclear receptor subfamily 1 group H member 3
• nuclear receptor subfamily 1, group H, member 3
• oxysterols receptor LXR-alpha
• RLD-1

Background

Liver X receptors (LXRs), also known as RLD1, are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous. The corresponding gene for the LXR alpha is NR1H3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR1H3
• Entrez:
  • 22259(Mouse)
• Uniprot:
  • Q9Z0Y9(Mouse)