LXR alpha/NR1H3 Antibody

Western Blot: LXR alpha/NR1H3 Antibody [H00010062-B01P] - Analysis of NR1H3 expression in human liver.

Immunocytochemistry/Immunofluorescence: LXR alpha/NR1H3 Antibody [H00010062-B01P] - Analysis of purified antibody to NR1H3 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: LXR alpha/NR1H3 Antibody [H00010062-B01P] - Analysis of NR1H3 expression in transfected 293T cell line by NR1H3 polyclonal antibody. Lane 1: NR1H3 transfected lysate(44.22 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

LXR alpha/NR1H3 Antibody Summary

• Immunogen: NR1H3 (AAH41172.1, 1 a.a. - 402 a.a.) full-length human protein. MPHSAGGTAGVGLEAAEPTALLTRAEPPSEPTEIRPQKRKKGPAPKMLGNELCSVCGDKASGFHYNVLSCEGCKGFFRRSVIKGAHYICHSGGHCPMDTYMRRKCQECRLRKCRQAGMREECVLSEEQIRLKKLKRQEEEQAHATSLPPRASSPPQILPQLSPEQLGMIEKLVAAQQQCNRRSFSDRLRVTPWPMAPDPHSREARQQRFAHFTELAIVSVQEIVDFAKQLPGFLQLSREDQIALLKTSAIEVMLLETSRRYNPGSESITFLKDFSYNREDFAKAGLQVEFINPIFEFSRAMNELQLNDAEFALLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSIHHPHDRLMFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE
• Specificity: Reacts with nuclear receptor subfamily 1, group H, member 3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: NR1H3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: This antibody is reactive against tissue and transfected lysate in western blot, immunofluorescence, and as a detection antibody in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LXR alpha/NR1H3 Antibody

• alpha
• Liver X receptor alpha
• liver X receptor-alpha
• LXR alpha
• LXRA
• NR1H3
• Nuclear receptor subfamily 1 group H member 3
• nuclear receptor subfamily 1, group H, member 3
• oxysterols receptor LXR-alpha
• RLD-1

Background

Liver X Receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of cholesterol metabolism and bile acids. Two known isoforms, alpha and beta, are differentially expressed. The alpha isoform is predominantly expressed in liver, whereas the beta isoform expression has been shown to be ubiquitous.

LXR antibodies are useful for lipid and cholesterol metabolism studies.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NR1H3
• Entrez:
  • 10062(Human)
• Uniprot:
  • AAH41172.1(Human)