Lubricin/PRG4 Antibody

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Lubricin/PRG4 Antibody Summary

Immunogen
Synthetic peptide derived from N terminal domain of PRG4 protein
Specificity
Reacts specifically with human 151 kDa protein
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PRG4
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:200-1:1000
  • Immunocytochemistry/Immunofluorescence 1:50 - 1:200
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
IHC-P, IHC reactivity reported in scientific literature (PMID: 23705804), (23083677).
Publications
Read Publications using
NBP1-19048 in the following applications:

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23705804)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Antiserum
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Lyophilized powder, reconstituted in distilled water.

Alternate Names for Lubricin/PRG4 Antibody

  • bG174L6.2 (MSF: megakaryocyte stimulating factor )
  • bG174L6.2
  • CACP
  • FLJ32635
  • JCAP
  • lubricin
  • megakaryocyte stimulating factor
  • Megakaryocyte-stimulating factor
  • MSFproteoglycan 4, (megakaryocyte stimulating factor, articular superficial zoneprotein, camptodactyly, arthropathy, coxa vara, pericarditis syndrome)
  • proteoglycan 4
  • Superficial zone proteoglycan
  • SZPHAPOarticular superficial zone protein

Background

Lubricin is a glycoprotein encoded by the PRG4 gene. It has been identified as a component of joint lubrication and synovial homeostasis by reducing friction in joints and preventing synovial cell overgrowth. It is a large, water soluble molecule that acts as a carrier for insoluble surface-active phospholipid (SAPL). Depletion of lubricin function has been associated with camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP), an arthritic-like autosomal recessive disorder.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Lubricin/PRG4 Antibody (NBP1-19048)(7)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: ICC/IF, IHC, IHC-P.


Filter By Application
ICC/IF
(1)
IHC
(4)
IHC-P
(1)
All Applications
Filter By Species
Human
(2)
Mouse
(3)
All Species

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Product General Protocols

View specific protocols for Lubricin/PRG4 Antibody (NBP1-19048): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Lubricin/PRG4 Antibody (NBP1-19048). (Showing 1 - 1 of 1 FAQs).

  1. Can I use the Proteoglycan 4 Antibody NBP1-19048 in rats tissues paraffined?
    • This antibody has not been tested for use in rat, however I have checked the percentage homology between the rat protein and the human protein and it is 96%. If you would be interested in testing this novel species, please take a look at our Innovators Reward Program.

Secondary Antibodies

 

Isotype Controls

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Additional Lubricin/PRG4 Products

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Diseases for Lubricin/PRG4 Antibody (NBP1-19048)

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Bioinformatics

Gene Symbol PRG4
Entrez
Uniprot