LRP-1B Antibody (1034124) [Alexa Fluor® 532]

• Applications: WB, IHC
• Clone: 1034124
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

LRP-1B Antibody (1034124) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived human LRP-1 Cluster II
  Gln4449-Ala4544
  Accession # Q07954
• Specificity: Detects human LRP-1 beta subunit in ELISA and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity. LRP-1 is an endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. It plays a crucial role in early embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.