LRP-1B Antibody (1034124) [Alexa Fluor® 488]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 1034124
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

LRP-1B Antibody (1034124) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived human LRP-1 Cluster II
  Gln4449-Ala4544
  Accession # Q07954
• Specificity: Detects human LRP-1 beta subunit in ELISA and Western blots.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LRP-1B Antibody (1034124) [Alexa Fluor® 488]

• EC 1.1.1.94
• EC 3.4.21.9
• low density lipoprotein receptor related protein-deleted in tumor
• low density lipoprotein receptor-related protein 1B
• low density lipoprotein-related protein 1B (deleted in tumors)
• Low-density lipoprotein receptor-related protein-deleted in tumor
• LRP1B
• LRP-1B
• LRP-deleted in tumors
• LRPDIT
• LRP-DIT
• LRP-DITlow-density lipoprotein receptor-related protein 1B

Background

LRP-1 (low-density lipoprotein receptor-related protein 1) is a large type I transmembrane protein belonging to the LDL receptor superfamily. The extracellular domain of LRP-1 is organized in four clusters of ligand-binding repeats that recognizes at least 30 different ligands. The amino acid sequence of human and mouse LRP-1 cluster II share 100% identity. LRP-1 is an endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. It plays a crucial role in early embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Uniprot:
  • Q07954(Human)