LPAR2/LPA2/EDG-4 Antibody [DyLight 650]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: DyLight 650

LPAR2/LPA2/EDG-4 Antibody [DyLight 650] Summary

• Immunogen: E. coli-derived recombinant human LPAR2
  Met1-Val33, His91-Gly103, Ser168-Ser188, Asp264-Tyr279
  Accession # Q9HBW0
• Specificity: Detects human LPAR2 in direct ELISAs and Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant human LPAR1 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: LPAR2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for LPAR2/LPA2/EDG-4 Antibody [DyLight 650]

• EDG4
• EDG-4
• EDG4FLJ93869
• endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor4,LPA receptor EDG4
• G protein-coupled receptor
• LPA2
• LPA-2
• LPA2LPA receptor 2
• LPAR2
• lysophosphatidic acid receptor 2
• lysophosphatidic acid receptor EDG4
• Lysophosphatidic acid receptor Edg-4

Background

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LPAR2