LPAR2/LPA2/EDG-4 Products

Description

Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.

Bioinformatics

Entrez	53978 Mouse 9170 Human
Uniprot	AAH25695 Human NM_004720 Human NP_004711 Human NP_004711.2 Human Q9HBW0 Human
Product By Gene ID	9170
Alternate Names	EDG-4 EDG4FLJ93869 endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor4,LPA receptor EDG4 G protein-coupled receptor LPA-2 LPA2LPA receptor 2 lysophosphatidic acid receptor 2 lysophosphatidic acid receptor EDG4 Lysophosphatidic acid receptor Edg-4

Research Areas for LPAR2/LPA2/EDG-4

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
DNA Repair
GPCR
Tumor Suppressors