LMTK2 Antibody (465222)

• Reactivity: Hu
• Applications: WB
• Clone: 465222
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Concentration: LYOPH

LMTK2 Antibody (465222) Summary

• Immunogen: E. coli-derived recombinant human LMTK2
  Ala93-Tyr284
  Accession # Q8IWU2
• Specificity: Detects human LMTK2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human AATK is observed.
• Source: N/A
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Rat
• Gene: LMTK2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LMTK2 Antibody (465222)

• AATK2
• AATYK2FLJ46659
• Apoptosis-associated tyrosine kinase 2
• Brain-enriched kinase
• BREK
• BREKCDK5/p35-regulated kinase
• CPRK
• EC 2.7.11
• KIAA1079hBREK
• kinase phosphatase inhibitor 2
• Kinase/phosphatase/inhibitor 2
• KPI-2
• KPI2EC 2.7.11.1
• lemur tyrosine kinase 2Serine/threonine-protein kinase KPI-2
• LMR2
• LMR2cyclin-dependent kinase 5/p35-regulated kinase
• LMTK2
• serine/threonine-protein kinase LMTK2

Background

LMTK2 (lemur tyrosine kinase 2), also known as KPI-2 (kinase/phosphatase inhibitor 2), cprk (cdk5-regulated kinase) or Brek (brain-enriched kinase), is a 210 kDa type I transmembrane ser/thr kinase that is a member of the lemur family of kinases with long (lemur-like) C-terminal cytoplasmic tails. It is expressed mainly in the brain and is enriched in perinatal neurons, but is also found in germ cells. Amino acids (aa) 93‑284 of human LMTK2 share 93% and 92% aa identity with mouse and rat LMTK2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LMTK2
• Uniprot:
  • Q8IWU2()