LMTK2 Products

Description

The protein encoded by the LMTK2 gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies suggested an essential role of this protein in spermatogenesis. (provided by RefSeq)

Bioinformatics

Product By Gene ID	22853
Alternate Names	AATK2 AATYK2FLJ46659 Apoptosis-associated tyrosine kinase 2 Brain-enriched kinase BREK BREKCDK5/p35-regulated kinase CPRK EC 2.7.11 KIAA1079hBREK kinase phosphatase inhibitor 2 Kinase/phosphatase/inhibitor 2 KPI-2 KPI2EC 2.7.11.1 lemur tyrosine kinase 2Serine/threonine-protein kinase KPI-2 LMR2 LMR2cyclin-dependent kinase 5/p35-regulated kinase LMTK2 serine/threonine-protein kinase LMTK2

Research Areas for LMTK2

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Protein Kinase