LIFR alpha Antibody (4A10)

Sandwich ELISA: LIFR alpha Antibody (4A10) [H00003977-M01] - Detection limit for recombinant GST tagged LIFR is approximately 0.03ng/ml as a capture antibody.

Product Discontinued

LIFR alpha Antibody (4A10) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: LIFR (NP_002301, 45 a.a. ~ 154 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QKKGAPHDLKCVTNNLQVWNCSWKAPSGTGRGTDYEVCIENRSRSCYQLEKTSIKIPALSHGDYEITINSLHDFGSSTSKFTLNEQNVSLIPDTPEILNLSADFSTSTLY
• Specificity: LIFR - leukemia inhibitory factor receptor (4A10)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: LIFR
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
• Application Notes: It has been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LIFR alpha Antibody (4A10)

• CD118 antigen
• CD118
• FLJ98106
• FLJ99923
• leukemia inhibitory factor receptor alpha
• leukemia inhibitory factor receptor
• LIF R alpha
• LIF R beta
• LIF receptor
• LIFR alpha
• LIFR
• LIF-R
• LIFRa
• SJS2
• STWS
• SWS

Background

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LIFR
• Entrez:
  • 3977(Human)
• Uniprot:
  • NP_002301()