Recombinant Human LBP Protein

Product Discontinued

Recombinant Human LBP Protein Summary

• Description: Recombinant bioactive protein for Human LBP
  
  

  Source:CHO cells
  Amino Acid Sequence:(P18428)

• Details of Functionality: Up to 0.2 ug/ ml LBP mediates binding of FITC-LPS (0.5ug/ml) to CD14+CHO transfectants (FACS).
• Source: CHO
• Protein/Peptide Type: Recombinant Protein
• Gene: LBP
• Purity: >95%, by SDS-PAGE
• Endotoxin Note: <0.03 ng/ ml

Applications/Dilutions

• Dilutions:
  • Bioactivity
  • SDS-Page
• Theoretical MW: 58 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20 to -80C. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from PBS (pH 7.1).
• Concentration: Lyoph
• Purity: >95%, by SDS-PAGE
• Reconstitution Instructions: Reconstitute in 40 ul of ultra-pure distilled H2O. This solution can then be diluted into other aqueous buffers and stored at -20C or -70C for long-term storage.

Alternate Names for Recombinant Human LBP Protein

• LBP
• lipopolysaccharide binding protein
• lipopolysaccharide-binding protein
• LPS-binding protein
• MGC22233

Background

Natural LBP is a 58 kDa glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1Beta, IL6, TNFa). It acts as opsonin for GRAM negative cells, LPS, neutrophils and granulocytes. This is a His-tagged protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: LBP