LATS2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: LATS2 Antibody - BSA Free [NBP3-46037] - Immunofluorescent analysis of HepG2 cells using (LATS2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L)

Western Blot: LATS2 Antibody - BSA Free [NBP3-46037] - SGC-7901 cells were subjected to SDS PAGE followed by western blot with (LATS2 antibody) at dilution of 1:500

Immunohistochemistry: LATS2 Antibody - BSA Free [NBP3-46037] - Immunohistochemistry of paraffin-embedded human heart using (LATS2 antibody) at dilution of 1:100

• Reactivity: Hu, Mu
• Applications: WB, ELISA, ICC/IF, IHC, NULL
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

LATS2 Antibody - BSA Free Summary

• Immunogen: LATS, large tumor suppressor, homolog 2. (Uniprot# Q9NRM7)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: LATS2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Serum FC
  • Western Blot 1:500-1:2000
• Theoretical MW: 150 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for LATS2 Antibody - BSA Free

• EC 2.7.11
• EC 2.7.11.1
• FLJ13161
• Kinase phosphorylated during mitosis protein
• KPM
• Large tumor suppressor homolog 2
• LATS (large tumor suppressor, Drosophila) homolog 2
• LATS, large tumor suppressor, homolog 2 (Drosophila)
• serine/threonine kinase KPM
• Serine/threonine-protein kinase kpm
• serine/threonine-protein kinase LATS2
• Warts-like kinase

Background

LATS2 encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LATS2