Lass5 Antibody

Images

 
Western Blot: Lass5 Antibody [NBP1-76964] - SK-N-SH lysate with LASS5 antibody at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry-Paraffin: Lass5 Antibody [NBP1-76964] - Mouse brain tissue with LASS5 antibody at 2.5 ug/ml.
Western Blot: Lass5 Antibody [NBP1-76964] - Human neuroblastoma cell lines untreated or treated with various drugs. Image from verified customer review.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Lass5 Antibody Summary

Immunogen
Antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human LASS5. The immunogen is located within the first 50 amino acids of LASS5.
Specificity
Multiple isoforms of LASS5 are known to exist. This antibody is predicted not to cross-react with the highly homologous LASS6.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CERS5
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
Lass5 Peptide (NBP1-76964PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Lass5 Antibody

  • CerS5
  • FLJ25304
  • LAG1 homolog, ceramide synthase 5
  • LAG1 longevity assurance homolog 5 (S. cerevisiae)
  • LAG1 longevity assurance homolog 5
  • MGC45411
  • Trh4

Background

The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein. Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner. It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide. LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia. Recent studies show that LASS5 partially correct growth and apoptosis. Multiple isoforms of LASS5 are known to exist. This antibody is predicted not to cross-react with the highly homologous LASS6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP1-92067
Species: Hu
Applications: ICC/IF, IHC, IHC-P
H00253782-A01
Species: Hu, Mu
Applications: WB, ELISA
NBP1-88927
Species: Hu
Applications: ICC/IF, IHC, IHC-P
H00029956-M01A
Species: Hu, Mu
Applications: WB, ELISA, IHC-P
H00728695-B01P
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P
NBP1-43435
Species: Hu, Mu
Applications: WB, Flow
H00079603-M03
Species: Hu
Applications: WB, ELISA, ICC/IF
NB600-1335
Species: Hu, Mu, Rt, Pm
Applications: WB, Simple Western, GS, ICC/IF, IHC, IHC-P, IP
H00008877-M01
Species: Hu
Applications: WB, ELISA
NBP1-86461
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-37399
Species: Hu
Applications: WB, ELISA, Flow, ICC/IF, IHC, CyTOF-ready
NBP1-85091
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP1-31649
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
H00002965-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P, RNAi
NBP2-02627
Species: Hu, Ca, Mk
Applications: WB, Flow, ICC/IF, IHC, IHC-P
NB100-2220
Species: Hu, Mu, Rt, Po, Ba, Bv, Ca, SyHa, Pm, Ze
Applications: WB, Simple Western, ELISA, IB, ICC/IF, IHC, IHC-Fr, IHC-P, IP, PLA, ChIP, KO
NBP1-28566
Species: Hu, Mu, Rt, Bv, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-Fr, IP

Publications for Lass5 Antibody (NBP1-76964) (0)

There are no publications for Lass5 Antibody (NBP1-76964).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Lass5 Antibody (NBP1-76964) (0)

There are no reviews for Lass5 Antibody (NBP1-76964). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Lass5 Antibody (NBP1-76964) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Lass5 Products

Bioinformatics Tool for Lass5 Antibody (NBP1-76964)

Discover related pathways, diseases and genes to Lass5 Antibody (NBP1-76964). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Lass5 Antibody (NBP1-76964)

Discover more about diseases related to Lass5 Antibody (NBP1-76964).
 

Pathways for Lass5 Antibody (NBP1-76964)

View related products by pathway.

PTMs for Lass5 Antibody (NBP1-76964)

Learn more about PTMs related to Lass5 Antibody (NBP1-76964).

Blogs on Lass5

There are no specific blogs for Lass5, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Lass5 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol CERS5
Uniprot