LASS1 Antibody

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Western Blot: LASS1 Antibody [NBP1-28480] - Staining of Frontal Cortex lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Detected by chemiluminescence.

Product Details

Summary
Reactivity Hu, Mu, Po, BvSpecies Glossary
Applications WB, PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

LASS1 Antibody Summary

Immunogen
Peptide with sequence C-KDLREYDTAEAQ corresponding to internal region according to NP_937850.1.
Epitope
C terminus
Specificity
This antibody is expected to recognize both reported isoforms (NP_067090.1and NP_937850.1).
Predicted Species
Mouse (100%), Porcine (100%), Bovine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
CERS1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:64000
  • Western Blot 1 - 3 ug/mL
Application Notes
WB: Approx. 37 kDa band observed in human brain (cerebellum, cerebral cortex and frontal cortex) lysates (calculated MW of 38.0 kDa band according to NP_937850.1). An additional band of unknown identity was also consistently observed at 85 kDa. This band was successfully blocked by incubation with the immunizing peptide.
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Publications
Read Publications using
NBP1-28480 in the following applications:

  • WB
    1 publication

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for LASS1 Antibody

  • CerS1
  • LAG1 homolog, ceramide synthase 1
  • LAG1 longevity assurance homolog 1
  • LAG1MGC90349
  • longevity assurance (LAG1, S. cerevisiae) homolog 1
  • Longevity assurance gene 1 protein homolog 1
  • Protein UOG-1
  • UOG1LAG1 longevity assurance homolog 1 (S. cerevisiae)
  • upstream of GDF1

Background

This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. Members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in yeast suggest that the encoded protein is involved in aging. This protein is transcribed from a monocistronic mRNA as well as a bicistronic mRNA, which also encodes growth differentiation factor 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LASS1 Antibody (NBP1-28480)(2)

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CERS1
Entrez
Uniprot